» Authors » P E Rolan

P E Rolan

Explore the profile of P E Rolan including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 28
Citations 311
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Johnson J, Rolan P, Johnson M, Bobrovskaya L, Williams D, Johnson K, et al.
Transl Psychiatry . 2014 Nov; 4:e482. PMID: 25386959
Chronic morphine therapy has been associated with paradoxically increased pain. Codeine is a widely used opioid, which is metabolized to morphine to elicit analgesia. Prolonged morphine exposure exacerbates pain by...
2.
Rolan P, Martin G
Expert Opin Investig Drugs . 2005 Jul; 7(4):633-52. PMID: 15992000
Zolmitriptan is a new oral acute treatment for migraine. It is a selective and potent agonist at the serotonin (5-HT)(1B/1D) receptor and was developed to improve on the oral bioavailability,...
3.
Moller S, Larsen F, Khant A, Rolan P
J Clin Psychopharmacol . 2001 Oct; 21(5):493-9. PMID: 11593075
Carbamazepine, a drug used in the treatment of seizure disorders, and citalopram, a highly selective serotonin reuptake inhibitor used for the treatment of depression and other psychiatric disorders, are both...
4.
Moller S, Larsen F, Pitsiu M, Rolan P
Clin Ther . 2001 Feb; 22(12):1494-501. PMID: 11192140
Background: Citalopram and theophylline may be prescribed together to treat patients with depression and asthmatic disease. Because theophylline has a low therapeutic index, small changes in plasma levels may result...
5.
Mercer A, Lamb R, Rolan P, Gibbens M, Posner J
Psychopharmacology (Berl) . 1999 Jan; 140(4):398-404. PMID: 9888613
The novel selective 5-hydroxytryptamine (5-HT)1B/1D agonist, zolmitriptan (Zomig, formerly known as 311C90), has shown good efficacy in the acute oral treatment of migraine. Zolmitriptan acts both centrally and peripherally, therefore...
6.
Peck R, Seaber E, Dixon R, Layton G, Weatherley B, Jackson S, et al.
Clin Pharmacol Ther . 1998 Apr; 63(3):342-53. PMID: 9542478
Objective: Zolmitriptan is a selective 5HT1B/1D-agonist for the treatment of migraine. In this study we investigated the cardiovascular and central nervous system effects and the pharmacokinetics of zolmitriptan in young...
7.
Dixon R, Meire H, Evans D, Watt H, On N, Posner J, et al.
Cephalalgia . 1997 Nov; 17(6):639-46. PMID: 9350383
Members of the new class of antimigraine compounds, 5HT1B/1D agonists, as well as ergotamine, may cause vasoconstriction through stimulation of 5HT receptors on peripheral vessels. The cardiovascular effects of 20...
8.
Brookman L, Rolan P, Benjamin I, Palmer K, Wyld P, Lloyd P, et al.
Clin Pharmacol Ther . 1997 Oct; 62(3):272-8. PMID: 9333102
Objectives: Valsartan (CGP 48933), an orally active angiotensin II antagonist, is eliminated mainly by hepatic clearance. To characterize the compound(s) excreted in the bile, biliary excretion of valsartan was investigated...
9.
Priskorn M, Sidhu J, Larsen F, Davis J, Khan A, Rolan P
Br J Clin Pharmacol . 1997 Aug; 44(2):199-202. PMID: 9278211
Aims: An open, controlled, randomized, crossover study was conducted in healthy males to assess the possible occurrence of a pharmacokinetic/pharmacodynamic interaction between warfarin and the selective serotonin re-uptake inhibitor citalopram....
10.
Lefevre G, Duval M, Gauron S, Brookman L, Rolan P, Morris T, et al.
Clin Pharmacol Ther . 1997 Jul; 62(1):50-9. PMID: 9246019
Objective: To investigate the pharmacokinetics and pharmacodynamics of desirudin in subjects with various degrees of renal impairment in comparison with subjects with normal renal function. Methods: Eight subjects with normal...