F Bochner
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Explore the profile of F Bochner including associated specialties, affiliations and a list of published articles.
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140
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1515
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Recent Articles
1.
La Vincente S, White J, Somogyi A, Bochner F, Chapleo C
Clin Pharmacol Ther
. 2007 Jun;
83(1):144-52.
PMID: 17568402
Animal studies have demonstrated that co-administration of an ultra-low-dose opioid antagonist with an opioid agonist may result in enhanced analgesia. Investigation of this effect in humans has been limited and...
2.
Chew M, White J, Somogyi A, Bochner F, Irvine R
Eur J Pharmacol
. 2001 Aug;
425(3):159-64.
PMID: 11513833
The role of metabolic polymorphism in the development of physical dependence to codeine was assessed in cytochrome P450 2D2 (CYP2D2) deficient Dark Agouti and CYP2D2 intact Sprague-Dawley rats by assessment...
3.
Dyer K, White J, Foster D, Bochner F, Menelaou A, Somogyi A
J Clin Psychopharmacol
. 2001 Feb;
21(1):78-84.
PMID: 11199952
Although methadone maintenance is designed to stabilize opioid-dependent patients, some experience significant withdrawal in the latter part of the 24-hour interdosing interval. This study was designed to determine the mood...
4.
Doverty M, White J, Somogyi A, Bochner F, Ali R, Ling W
Pain
. 2001 Feb;
90(1-2):91-6.
PMID: 11166974
Opioid substitution treatment for dependence may alter sensitivity to pain. Previous studies on pain sensitivity in methadone maintenance patients have yielded contradictory results. This study compared nociceptive responses between 16...
5.
Foster D, Somogyi A, Dyer K, White J, Bochner F
Br J Clin Pharmacol
. 2000 Nov;
50(5):427-40.
PMID: 11069437
Aims: To investigate the steady-state pharmacokinetics of (R)- and (S)-methadone in a methadone maintenance population. Methods: Eighteen patients recruited from a public methadone maintenance program underwent an interdosing interval pharmacokinetic...
6.
Daws L, Irvine R, Callaghan P, Toop N, White J, Bochner F
Prog Neuropsychopharmacol Biol Psychiatry
. 2000 Oct;
24(6):955-77.
PMID: 11041537
1. This study was prompted by recent deaths that have occurred after recreational administration of the substituted amphetamine para-methoxyamphetamine (PMA). Because relatively little is known regarding its mechanism(s) of action,...
7.
Foster D, Somogyi A, Bochner F
J Chromatogr B Biomed Sci Appl
. 2000 Sep;
744(1):165-76.
PMID: 10985578
A stereoselective HPLC assay was developed for the quantification of the enantiomers of methadone and its major oxidative metabolite, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) in human urine. The compounds were quantified in a...
8.
Coller J, Somogyi A, Bochner F
Xenobiotica
. 1999 Nov;
29(10):973-86.
PMID: 10574680
The aims were to examine the kinetics of the oxidative metabolism of flunitrazepam in vitro when flunitrazepam was dissolved in dimethylformamide and acetonitrile, and to determine which cytochrome P450 isoform(s)...
9.
Menelaou A, Somogyi A, Barclay M, Bochner F
J Chromatogr B Biomed Sci Appl
. 1999 Oct;
731(2):261-6.
PMID: 10510779
A simple, robust HPLC method was developed to measure simultaneously the plasma concentrations of amoxycillin and metronidazole in order to assess their disposition in the eradication of Helicobacter pylori. Plasma...
10.
Malpass A, White J, Irvine R, Somogyi A, Bochner F
Pharmacol Biochem Behav
. 1999 Sep;
64(1):29-34.
PMID: 10494994
Ingestion of MDMA ("ecstasy") by humans can cause acute toxicity manifested by hyperthermia and death. Demethylenation of MDMA is catalyzed by cytochrome P-450 2D6 (CYP2D6) and cytochrome P-450 2D1 (CYP2D1)...