P DOrleans-Juste
Overview
Explore the profile of P DOrleans-Juste including associated specialties, affiliations and a list of published articles.
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Articles
148
Citations
1371
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Recent Articles
1.
Carrier E, Houde M, Grandbois M, Bkaily G, Warner T, DOrleans-Juste P
Can J Physiol Pharmacol
. 2017 Jul;
95(8):954-960.
PMID: 28704616
In the present study, we assessed whether the endogenous platelet inhibitory mechanisms are altered in the early to moderate stages of the atherosclerotic process. Apolipoprotein E deficient mice (ApoE-/-), a...
2.
Houde M, Desbiens L, DOrleans-Juste P
Adv Pharmacol
. 2016 Jul;
77:143-75.
PMID: 27451097
Endothelin-1 (ET-1) is an extremely potent vasoconstrictor peptide originally isolated from endothelial cells. Its synthesis, mainly regulated at the gene transcription level, involves processing of a precursor by a furin-type...
3.
Brochu I, Houde M, Desbiens L, Simard E, Gobeil F, Semaan W, et al.
Br J Pharmacol
. 2013 May;
170(2):266-77.
PMID: 23713522
Background And Purpose: The contribution of endothelin-1 (ET-1) in a B2KO mouse model of a high salt-induced arterial hypertension was investigated. Experimental Approach: Wild-type (WT) or B2KO mice receiving a...
4.
DOrleans-Juste P, Houde M, Rae G, Bkaily G, Carrier E, Simard E
Vascul Pharmacol
. 2008 Aug;
49(2-3):51-62.
PMID: 18675382
The mast cell-derived serine protease chymase is importantly involved not only in degradation, but in synthesis of bioactive peptides as well. Several studies suggest that chymase is the predominant enzyme...
5.
Tirapelli C, Legros E, Brochu I, Honore J, Lanchote V, Uyemura S, et al.
Br J Pharmacol
. 2008 May;
154(5):971-81.
PMID: 18469849
Background And Purpose: The contribution of endothelin-1 (ET-1) to vascular hyper-reactivity associated with chronic ethanol intake, a major risk factor in several cardiovascular diseases, remains to be investigated. Experimental Approach:...
6.
Legros E, Tirapelli C, Carrier E, Brochu I, Fournier A, DOrleans-Juste P
Br J Pharmacol
. 2007 Oct;
152(7):1049-59.
PMID: 17906682
Background And Purpose: Calcitonin gene-related peptide (CGRP), a capsaicin-sensitive neuromodulator of splanchnic vascular tone in several animal species, remains poorly investigated in mouse models. We therefore assessed whether endogenous CGRP...
7.
Teixeira C, Jancar S, Lima W, DOrleans-Juste P, Sirois P
Inflammation
. 2005 Sep;
28(5):253-61.
PMID: 16133998
The participation of endothelins (ETs) in a model of neutrophil-dependent lung injury induced by intrabronchial instillation of rabbit antibodies to ovalbumin followed by i.v. injection of the antigens (Arthus reaction)...
8.
DOrleans-Juste P, Plante M, Honore J, Carrier E, Labonte J
Can J Physiol Pharmacol
. 2003 Jul;
81(6):503-10.
PMID: 12839262
The endothelin-converting enzyme (ECE) is the main enzyme responsible for the genesis of the potent pressor peptide endothelin-1 (ET-1). It is suggested that the ECE is pivotal in the genesis...
9.
Bkaily G, Sleiman S, Stephan J, Asselin C, Choufani S, Kamal M, et al.
Can J Physiol Pharmacol
. 2003 May;
81(3):274-87.
PMID: 12733826
The present study was designed to verify if human (h) Angiotensin II (Ang II) type-1 receptor (hAT1R) undergoes internalization, nuclear translocation, and de novo synthesis in primary culture of human...
10.
DOrleans-Juste P, Labonte J, Bkaily G, Choufani S, Plante M, Honore J
Pharmacol Ther
. 2002 Sep;
95(3):221-38.
PMID: 12243796
One of the two receptors by which the potent vasoactive effects of endothelin (ET)-1 are mediated is the ET(B) receptor (ET(BR)), which is found in several tissues, but, more importantly...