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P D Gershon

Explore the profile of P D Gershon including associated specialties, affiliations and a list of published articles. Areas
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Articles 48
Citations 864
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Recent Articles
1.
Matson J, Chou W, Ngo T, Gershon P
Virology . 2014 Mar; 452-453:310-23. PMID: 24606709
To the best of our knowledge, two phosphorylation sites have been reported previously, among 11 known Vaccinia virus phosphoproteins. Here, via phosphopeptide mass spectrometry, up to 189 phosphorylation sites were...
2.
Gershon P
Rapid Commun Mass Spectrom . 2010 Nov; 24(23):3373-9. PMID: 21072792
Two tools are described for integrating LC elution position with mass-based data in hydrogen-deuterium exchange (HDX) experiments by nano-liquid chromatography/matrix-assisted laser desorption/ionization mass spectrometry (nanoLC/MALDI-MS, a novel approach to HDX-MS)....
3.
Li C, Koter M, Ye X, Zhou S, Chou W, Luo R, et al.
Biochemistry . 2010 May; 49(29):6247-62. PMID: 20469877
Vaccinia virus poly(A) polymerase (VP55) has been analyzed via hydrogen-deuterium exchange (HDX) mass spectrometry in the absence and presence of its processivity factor, VP39, to improve our understanding of the...
4.
Kuznetsov Y, Gershon P, McPherson A
J Virol . 2008 May; 82(15):7551-66. PMID: 18508898
Vaccinia virus was treated in a controlled manner with various combinations of nonionic detergents, reducing agents, and proteolytic enzymes, and successive products of the reactions were visualized using atomic force...
5.
Kolomenskii A, Gershon P, Schuessler H
Appl Opt . 2008 Mar; 39(19):3314-20. PMID: 18349899
The effect of absorption of the sample medium on the surface-plasmon resonance (SPR) characteristics is analyzed by approximate analytical and exact numerical models. We show that absorption leads to specific...
6.
Kolomenskii A, Gershon P, Schuessler H
Appl Opt . 2008 Feb; 36(25):6539-47. PMID: 18259515
The shot noise limitation as well as other factors that influence the sensitivity of measurements with a surface plasmon resonance (SPR) sensor are considered. It is demonstrated that minute changes...
7.
Li C, Gershon P
Biochemistry . 2006 Jan; 45(3):907-17. PMID: 16411767
We have characterized the side chain pKa for a single lysine analogue within a 316-residue protein containing 21 lysines and 1678 carbon atoms at natural isotope abundance. To do this,...
8.
Li C, Xia Y, Gao X, Gershon P
Biochemistry . 2004 May; 43(19):5680-7. PMID: 15134442
The weight of current evidence suggests that RNA 2'-O-MTases employ an S(N)2 mechanism with an in-line attack of the target nucleophile upon the methyl group of the AdoMet cofactor. It...
9.
Johnson L, Liu S, Gershon P
J Mol Biol . 2004 Mar; 337(4):843-56. PMID: 15033355
Little is known regarding the translocation of non-templated nucleic acid polymerases with respect to single-stranded primers. VP55, the vaccinia virus poly(A) polymerase, translocates as it processively adds a approximately 3-7...
10.
Malkin A, McPherson A, Gershon P
J Virol . 2003 May; 77(11):6332-40. PMID: 12743290
Vaccinia virus, the basis of the smallpox vaccine, is one of the largest viruses to replicate in humans. We have used in situ atomic force microscopy (AFM) to directly visualize...