P Costelli
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Explore the profile of P Costelli including associated specialties, affiliations and a list of published articles.
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57
Citations
1511
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Recent Articles
11.
Costelli P, Aoki P, Zingaro B, Carbo N, Reffo P, Lopez-Soriano F, et al.
Cell Death Differ
. 2003 Aug;
10(9):997-1004.
PMID: 12934074
The liver is particularly susceptible to Fas-mediated cytotoxicity. Mice given an adequate parenteral dose of agonistic anti-Fas antibody (aFas) or of FasL are known to develop a devastating liver injury...
12.
Costelli P, Bossola M, Muscaritoli M, Grieco G, Bonelli G, Bellantone R, et al.
Cytokine
. 2002 Aug;
19(1):1-5.
PMID: 12200106
The ascites hepatoma Yoshida AH-130 induces loss of body weight and tissue waste. Tumour necrosis factor alpha (TNF-alpha) plays a pivotal role in the pathogenesis of muscle wasting in this...
13.
Bossola M, Muscaritoli M, Costelli P, Bellantone R, Pacelli F, Busquets S, et al.
Am J Physiol Regul Integr Comp Physiol
. 2001 Apr;
280(5):R1518-23.
PMID: 11294777
The intramuscular ATP-dependent ubiquitin (Ub)-proteasome proteolytic system is hyperactivated in experimental cancer cachexia. The present study aimed at verifying whether the expression of the muscle Ub mRNA is altered in...
14.
Carbo N, Lopez-Soriano J, Costelli P, Alvarez B, Busquets S, Baccino F, et al.
Biochim Biophys Acta
. 2001 Apr;
1526(1):17-24.
PMID: 11287118
Interleukin (IL)-15 is a cytokine which is highly expressed in skeletal muscle. Cell culture studies have indicated that IL-15 may have an important role in muscle fiber growth and anabolism....
15.
Costelli P, De Tullio R, Baccino F, Melloni E
Br J Cancer
. 2001 Apr;
84(7):946-50.
PMID: 11286475
Cachexia is a syndrome characterized by profound tissue wasting that frequently complicates malignancies. In a cancer cachexia model we have shown that protein depletion in the skeletal muscle, which is...
16.
Carbo N, Lopez-Soriano J, Costelli P, Busquets S, Alvarez B, Baccino F, et al.
Br J Cancer
. 2000 Aug;
83(4):526-31.
PMID: 10945502
Tissue protein hypercatabolism (TPH) is an important feature in cancer cachexia, particularly with regard to the skeletal muscle. The Yoshida AH-130 rat ascites hepatoma is a model system for studying...
17.
Costelli P, Baccino F
Curr Opin Clin Nutr Metab Care
. 2000 Jun;
3(3):177-81.
PMID: 10871232
Cachexia is frequently associated with advanced or terminal cancer states, but it can also develop early during the course of neoplastic disease. This syndrome, which is characterized by body weight...
18.
Costelli P, Tessitore L, Batetta B, Mulas M, Spano O, Pani P, et al.
J Nutr
. 1999 Mar;
129(3):700-6.
PMID: 10082777
The ascites hepatoma Yoshida AH130 causes in the host a rapid and progressive body weight loss, associated with reduced food intake, and protein and lipid hypercatabolism. Because insulin regulates glucose...
19.
Argiles J, Costelli P, Carbo N, Lopez-Soriano F
Int J Oncol
. 1999 Feb;
14(3):479-86.
PMID: 10024680
Tumour growth is frequently associated with massive loss of body weight and negative nitrogen balance leading to cachexia, one of the worst features of malignancy accounting for nearly two thirds...
20.
Llovera M, Carbo N, Lopez-Soriano J, Busquets S, Alvarez B, Agell N, et al.
Cancer Lett
. 1999 Feb;
133(1):83-7.
PMID: 9929164
Intravenous administration of different cytokines caused important changes in the expression of ubiquitin genes in skeletal muscle. Tumour necrosis factor-alpha caused a 2.2- and 1.9-fold increase in the expression of...