P A Schilderman
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Explore the profile of P A Schilderman including associated specialties, affiliations and a list of published articles.
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20
Citations
173
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Recent Articles
1.
Besaratinia A, Besarati Nia A, Schooten F, Schilderman P, de Kok T, Haenen G, et al.
Carcinogenesis
. 2001 Mar;
22(3):395-401.
PMID: 11238178
We investigated the effects of smoking-induced oxidative stress in healthy volunteers (21 smokers versus 24 non-smokers) by quantifying various markers of oxidative DNA damage and repair, and antioxidative defense mechanisms....
2.
Schilderman P, Maas L, Pachen D, de Kok T, Kleinjans J, Schooten F
Environ Mol Mutagen
. 2000 Oct;
36(2):79-86.
PMID: 11013405
It is known that lower-chlorinated biphenyls are metabolically activated to electrophilic quinoid species capable of binding to DNA. Also, certain metabolites are capable of redox cycling, thereby increasing oxidative stress...
3.
Zwingmann I, Welle I, Engelen J, Schilderman P, de Jong J, Kleinjans J
Mutat Res
. 2000 Jan;
431(2):361-9.
PMID: 10636001
Various markers of radiation-induced DNA damage including DNA oxidation were investigated in peripheral lymphocytes of 23 cancer patients prior to and one week after receiving radiotherapy with a cumulative dose...
4.
Godschalk R, Moonen E, Schilderman P, Broekmans W, Kleinjans J, Schooten F
Carcinogenesis
. 1999 Dec;
21(1):87-92.
PMID: 10607738
Understanding the kinetics of aromatic-DNA adducts in target tissues and white blood cells (WBC) would enhance the applicability of DNA adducts in WBC as surrogate source of DNA in biomonitoring...
5.
Schilderman P, Moonen E, Maas L, Welle I, Kleinjans J
Ecotoxicol Environ Saf
. 1999 Dec;
44(3):241-52.
PMID: 10581118
The river Meuse, located in western Europe, is contaminated by different pollutants, of both organic and inorganic nature. The predominant sources of Meuse contamination in The Netherlands are agricultural activities...
6.
Van Maanen J, Borm P, Knaapen A, van Herwijnen M, Schilderman P, Smith K, et al.
Inhal Toxicol
. 1999 Nov;
11(12):1123-41.
PMID: 10562700
Oxygen radical generation due to surface radicals, inflammation, and iron release has been suggested as the mechanism of adverse effects of quartz, such as emphysema, fibrosis, and carcinogenic effects. Therefore,...
7.
Knaapen A, Seiler F, Schilderman P, Nehls P, Bruch J, Schins R, et al.
Free Radic Biol Med
. 1999 Aug;
27(1-2):234-40.
PMID: 10443941
Inflammation has been recognized as a contributing factor in the pathogenesis of some cancers. In the lung, inflammation is characterized by an influx of polymorphonuclear leukocytes (PMN) that release a...
8.
Zwingmann I, Welle I, van Herwijnen M, Engelen J, Schilderman P, Smid T, et al.
Environ Mol Mutagen
. 1998 Oct;
32(2):121-9.
PMID: 9776174
This study set out to analyze biomarkers for genotoxic events, e.g., oxidative DNA damage, chromosomal damage and hprt mutations, among flight personnel, who are known to be occupationally exposed to...
9.
Godschalk R, Vermeer I, KRIEK E, Floot B, Schilderman P, Moonen E, et al.
Chem Biol Interact
. 1997 Apr;
104(1):41-54.
PMID: 9158694
DNA adduct analysis is often used for biomonitoring individuals exposed to polycyclic aromatic hydrocarbons (PAH). The 32P-postlabeling assay is routinely applied to study the formation of aromatic bulky adducts, but...
10.
Schilderman P, Hoogewerff J, Schooten F, Maas L, Moonen E, van Os B, et al.
Environ Health Perspect
. 1997 Mar;
105(3):322-30.
PMID: 9171994
Wild city pigeons were caught at four different locations in the Netherlands to represent areas of high (Amsterdam-high), moderate (Amsterdam-medium), and low (Maastricht and Assen) traffic density. It is assumed...