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P A Brex

Explore the profile of P A Brex including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 763
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Recent Articles
1.
Giovannoni G, Brex P, Dhiraj D, Fullarton J, Freddi M, Rodgers-Gray B, et al.
Mult Scler J Exp Transl Clin . 2019 Dec; 5(4):2055217319893103. PMID: 31839981
Background: The UK Risk Sharing Scheme (RSS) provided information on the effect of first-line multiple sclerosis (MS) disease-modifying treatments on long-term disability. Objective: The aim is to provide results specific...
2.
Absoud M, Gadian J, Hellier J, Brex P, Ciccarelli O, Giovannoni G, et al.
BMJ Open . 2015 May; 5(5):e008312. PMID: 26009577
Introduction: Transverse myelitis (TM) is an immune-mediated disorder of the spinal cord which causes motor and sensory disturbance and limited recovery in 50% of patients. Standard treatment is steroids, and...
3.
Fisniku L, Brex P, Altmann D, Miszkiel K, Benton C, Lanyon R, et al.
Brain . 2008 Feb; 131(Pt 3):808-17. PMID: 18234696
Clinically isolated syndromes (CIS), such as optic neuritis, brainstem or spinal cord syndromes are frequently the first clinical presentations of multiple sclerosis. However, not all CIS patients develop multiple sclerosis...
4.
Traboulsee A, Dehmeshki J, Peters K, Griffin C, Brex P, Silver N, et al.
Mult Scler . 2003 Dec; 9(6):566-73. PMID: 14664468
Background: Magnetization transfer ratio (MTR) histogram analysis provides a global measure of disease burden in multiple sclerosis (MS). MTR abnormalities in normal appearing brain tissue (NABT) provide quantitative information on...
5.
Dalton C, Brex P, Miszkiel K, Fernando K, MacManus D, Plant G, et al.
J Neurol Neurosurg Psychiatry . 2003 Nov; 74(11):1577-80. PMID: 14617723
Background/methods: One hundred and fifteen patients with clinically isolated optic neuritis underwent magnetic resonance imaging (MRI) of the brain and spinal cord within 3 months of the onset of symptoms....
6.
Chard D, Brex P, Ciccarelli O, Griffin C, Parker G, Dalton C, et al.
J Neurol Neurosurg Psychiatry . 2003 Nov; 74(11):1551-4. PMID: 14617714
Background: Studies have suggested that T2 lesion activity is prominent in early relapsing-remitting multiple sclerosis, whereas brain atrophy, while seen early, appears more evident in later progressive disease. The temporal...
7.
Leary S, Miller D, Stevenson V, Brex P, Chard D, Thompson A
Neurology . 2003 Jan; 60(1):44-51. PMID: 12525716
Background: Patients with primary progressive MS have atypical clinical and MRI characteristics and have been excluded from most therapeutic trials. The authors report a randomized, controlled trial restricted to primary...
8.
Hickman S, Brierley C, Brex P, MacManus D, Scolding N, Compston D, et al.
Mult Scler . 2002 Aug; 8(4):339-42. PMID: 12166505
To investigate optic neuritis as a model for atrophy in multiple sclerosis (MS) lesions we performed serial magnetic resonance imaging (MRI) on 10 patients with a history of optic neuritis...
9.
Dalton C, Brex P, Jenkins R, Fox N, Miszkiel K, Crum W, et al.
J Neurol Neurosurg Psychiatry . 2002 Jul; 73(2):141-7. PMID: 12122170
Background: In patients with clinically isolated syndromes (CIS) suggestive of multiple sclerosis (MS), the extent of brain magnetic resonance imaging (MRI) lesion load influences the probability and time to development...
10.
Kapeller P, Brex P, Chard D, Dalton C, Griffin C, McLean M, et al.
Mult Scler . 2002 Jul; 8(3):207-10. PMID: 12120691
clinically isolated syndromes (CIS) are events suggestive for emerging multiple sclerosis (MS). A majority of patients develop MS within months or years whilst others remain clinically isolated. The goal of...