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S M Leary

Explore the profile of S M Leary including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 460
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Recent Articles
1.
Rejdak K, Leary S, Petzold A, Thompson A, Miller D, Giovannoni G
Mult Scler . 2010 Jul; 16(9):1066-72. PMID: 20639271
Background: Interferon beta has not been demonstrated to be effective in exploratory phase 2 clinical trials in primary progressive multiple sclerosis. However, using more sensitive indicators of a treatment response,...
2.
Leary S, Liu C, Cheesman A, Ritter A, Thompson S, Greenwood R
Clin Rehabil . 2006 Dec; 20(12):1094-9. PMID: 17148521
Objective: To investigate the prevalence, outcome and multidisciplinary management of incontinence in patients with acquired brain injury. Design: Retrospective case notes review. Setting: Regional neurological rehabilitation unit. Subjects: Two hundred...
3.
Leary S, Gilpin P, Lockley L, Rodriguez L, Jarrett L, Stevenson V
Clin Rehabil . 2006 Apr; 20(3):228-31. PMID: 16634341
Objective: To assess the effect of intrathecal baclofen on spastic dysarthia in cerebral palsy. Design: Single case study. Methods: Functional outcome measures, including the Assessment of Intelligibility of Dysarthric Speech,...
4.
Sastre-Garriga J, Ingle G, Rovaris M, Tellez N, Jasperse B, Altmann D, et al.
Neurology . 2005 Aug; 65(4):633-5. PMID: 16116134
The authors sought to identify clinical and MRI predictors of outcome in primary progressive multiple sclerosis (PPMS). Clinical and MRI assessments were performed at baseline and 2 and 5 years...
5.
Leary S, Porter B, Thompson A
Postgrad Med J . 2005 May; 81(955):302-8. PMID: 15879043
Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system that may result in a wide range of neurological symptoms and accumulating disability. Its course is unpredictable resulting...
6.
Leary S, Thompson A
J Neurol Neurosurg Psychiatry . 2004 Feb; 75(3):508-9. PMID: 14966181
No abstract available.
7.
Dehmeshki J, Chard D, Leary S, Watt H, Silver N, Tofts P, et al.
J Neurol . 2003 Jan; 250(1):67-74. PMID: 12527995
Background: In 10-15 % of patients with multiple sclerosis (MS), the clinical course is characterized by slow progression in disability without relapses (primary progressive (PP) MS). The mechanism of disability...
8.
Leary S, Miller D, Stevenson V, Brex P, Chard D, Thompson A
Neurology . 2003 Jan; 60(1):44-51. PMID: 12525716
Background: Patients with primary progressive MS have atypical clinical and MRI characteristics and have been excluded from most therapeutic trials. The authors report a randomized, controlled trial restricted to primary...
9.
Mann C, Davies M, Stevenson V, Leary S, Boggild M, Ko Ko C, et al.
J Neuroimmunol . 2002 Aug; 129(1-2):197-204. PMID: 12161036
We studied the association between clinical outcome in MS and allelic variants single nucleotide polymorphisms (SNPs) of interleukin-1alpha (IL-1alpha), IL-1beta and a variable number tandem repeat (VNTR) in IL-1 receptor...
10.
Ingle G, Stevenson V, Miller D, Leary S, Rovaris M, Barkhof F, et al.
Mult Scler . 2002 May; 8(2):108-14. PMID: 11990866
This study documents changes in clinical and magnetic resonance imaging (MRI) characteristics in a large cohort of patients with primary and transitional progressive multiple sclerosis (PP and TPMS) over 2...