Oxana Doroshyenko
Overview
Explore the profile of Oxana Doroshyenko including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
15
Citations
425
Followers
0
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Related Specialties
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Recent Articles
1.
Arshad U, Ploylearmsaeng S, Karlsson M, Doroshyenko O, Langer D, Schomig E, et al.
Cancer Chemother Pharmacol
. 2020 Mar;
85(4):711-722.
PMID: 32152679
Purpose: To describe 5-fluorouracil (5FU) pharmacokinetics, myelotoxicity and respective covariates using a simultaneous nonlinear mixed effect modelling approach. Methods: Thirty patients with gastrointestinal cancer received 5FU 650 or 1000 mg/m/day...
2.
Doroshyenko O, Rokitta D, Zadoyan G, Klement S, Schlafke S, Dienel A, et al.
Drug Metab Dispos
. 2013 Feb;
41(5):987-93.
PMID: 23401474
Unlabelled: This cocktail study evaluated the interaction potential of the oral lavender oil preparation silexan with major P450 (cytochrome P450) enzymes. Subjects And Methods: Sixteen healthy male or female Caucasians...
3.
Watzek N, Scherbl D, Feld J, Berger F, Doroshyenko O, Fuhr U, et al.
Mol Nutr Food Res
. 2012 Oct;
56(12):1825-37.
PMID: 23109489
Scope: Acrolein (AC) and acrylamide (AA) are food contaminants generated by heat treatment. We studied human exposure after consumption of potato crisps by monitoring excretion of mercapturic acids (MAs) in...
4.
Di Gion P, Kanefendt F, Lindauer A, Scheffler M, Doroshyenko O, Fuhr U, et al.
Clin Pharmacokinet
. 2011 Aug;
50(9):551-603.
PMID: 21827214
Pyrimidine (imatinib, dasatinib, nilotinib and pazopanib), pyridine (sorafenib) and pyrrole (sunitinib) tyrosine kinase inhibitors (TKIs) are multi-targeted TKIs with high activity towards several families of receptor and non-receptor tyrosine kinases...
5.
Scheffler M, Di Gion P, Doroshyenko O, Wolf J, Fuhr U
Clin Pharmacokinet
. 2011 May;
50(6):371-403.
PMID: 21553932
The 4-anilinoquinazolines (gefitinib, erlotinib and lapatinib) are members of a class of potent and selective inhibitors of the human epidermal growth factor receptor (HER) family of tyrosine kinases that have...
6.
Tomalik-Scharte D, Fuhr U, Hellmich M, Frank D, Doroshyenko O, Jetter A, et al.
Drug Metab Dispos
. 2011 Jan;
39(5):927-32.
PMID: 21270106
The pharmacokinetics of repaglinide shows pronounced interindividual variability, for which several reasons have been considered, including interactions with drugs inhibiting CYP2C8 and CYP2C8 genetic polymorphism. However, existing data on the...
7.
Jetter A, Fatkenheuer G, Frank D, Klaassen T, Seeringer A, Doroshyenko O, et al.
Antivir Ther
. 2010 Nov;
15(7):975-83.
PMID: 21041912
Background: In inflammation and infection, cytochrome P450 (CYP) enzyme activities are down-regulated. Information on possible discrepancies in activities of CYP enzymes and drug transporters between HIV-infected patients and healthy people...
8.
Queckenberg C, Meins J, Wachall B, Doroshyenko O, Tomalik-Scharte D, Bastian B, et al.
Antimicrob Agents Chemother
. 2009 Oct;
54(1):570-2.
PMID: 19822703
We evaluated the pharmacokinetics and safety of the antimicrobial agent triclosan after dermal application of a 2% triclosan-containing cream to six volunteers. Percutaneous absorption calculated from urinary excretion was 5.9%...
9.
Doroshyenko O, Fuhr U
Clin Pharmacokinet
. 2009 Jul;
48(5):281-302.
PMID: 19566112
The succinate salt of solifenacin, a tertiary amine with anticholinergic properties, is used for symptomatic treatment of overactive bladder. Solifenacin peak plasma concentrations of 24.0 and 40.6 ng/mL are reached...
10.
Doroshyenko O, Fuhr U, Kunz D, Frank D, Kinzig M, Jetter A, et al.
Cancer Epidemiol Biomarkers Prev
. 2009 Feb;
18(2):433-43.
PMID: 19190172
Acrylamide, a potential food carcinogen in humans, is biotransformed to the epoxide glycidamide in vivo. Both acrylamide and glycidamide are conjugated with glutathione, possibly via glutathione-S-transferases (GST), and bind covalently...