Owen Pornillos
Overview
Explore the profile of Owen Pornillos including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
52
Citations
3255
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
21.
Sundquist W, Pornillos O
Cell Host Microbe
. 2018 Dec;
24(6):751-753.
PMID: 30543772
The restriction factor TRIM5α recognizes incoming retroviral capsids and blocks virus replication. In this issue of Cell Host & Microbe, Fletcher et al. (2018) show how the TRIM5α RING domain...
22.
Sanchez J, Sparrer K, Chiang C, Reis R, Chiang J, Zurenski M, et al.
J Mol Biol
. 2018 Oct;
430(24):5280-5293.
PMID: 30342007
TRIM25 is a multi-domain, RING-type E3 ubiquitin ligase of the tripartite motif family that has important roles in multiple RNA-dependent processes. In particular, TRIM25 functions as an effector of RIG-I...
23.
Dick R, Zadrozny K, Xu C, Schur F, Lyddon T, Ricana C, et al.
Nature
. 2018 Aug;
563(7731):E22.
PMID: 30158708
In this Letter, the Protein Data Bank (PDB) accessions were incorrectly listed as '6BH5, 6BHT and 6BHS' instead of '6BHR, 6BHT and 6BHS'; this has been corrected online.
24.
Dick R, Zadrozny K, Xu C, Schur F, Lyddon T, Ricana C, et al.
Nature
. 2018 Aug;
560(7719):509-512.
PMID: 30069050
A short, 14-amino-acid segment called SP1, located in the Gag structural protein, has a critical role during the formation of the HIV-1 virus particle. During virus assembly, the SP1 peptide...
25.
Buffone C, Martinez-Lopez A, Fricke T, Opp S, Severgnini M, Cifola I, et al.
J Virol
. 2018 Jul;
92(19).
PMID: 29997211
Human immunodeficiency virus type 1 (HIV-1) displays the unique ability to infect nondividing cells. The capsid of HIV-1 is the viral determinant for viral nuclear import. To understand the cellular...
26.
Wagner J, Christensen D, Bhattacharya A, Dawidziak D, Roganowicz M, Wan Y, et al.
J Virol
. 2017 Dec;
92(4).
PMID: 29187540
Restriction factors are intrinsic cellular defense proteins that have evolved to block microbial infections. Retroviruses such as HIV-1 are restricted by TRIM5 proteins, which recognize the viral capsid shell that...
27.
Roganowicz M, Komurlu S, Mukherjee S, Plewka J, Alam S, Skorupka K, et al.
PLoS Pathog
. 2017 Oct;
13(10):e1006686.
PMID: 29040325
Restriction factors are important components of intrinsic cellular defense mechanisms against viral pathogens. TRIM5α is a restriction factor that intercepts the incoming capsid cores of retroviruses such as HIV and...
28.
Sparrer K, Gableske S, Zurenski M, Parker Z, Full F, Baumgart G, et al.
Nat Microbiol
. 2017 Sep;
2(11):1543-1557.
PMID: 28871090
Autophagy and interferon (IFN)-mediated innate immunity are critical antiviral defence mechanisms, and recent evidence indicated that tripartite motif (TRIM) proteins are important regulators of both processes. Although the role of...
29.
Dawidziak D, Sanchez J, Wagner J, Ganser-Pornillos B, Pornillos O
Proteins
. 2017 Jul;
85(10):1957-1961.
PMID: 28681414
Tripartite motif (TRIM) proteins comprise a large family of RING-type ubiquitin E3 ligases that regulate important biological processes. An emerging general model is that TRIMs form elongated antiparallel coiled-coil dimers...
30.
Janczyk P, Skorupka K, Tooley J, Matson D, Kestner C, West T, et al.
Dev Cell
. 2017 May;
41(4):438-449.e4.
PMID: 28535377
Yeast use the ring-shaped Dam1 complex to slide down depolymerizing microtubules to move chromosomes, but current models suggest that other eukaryotes do not have a sliding ring. We visualized Ndc80...