Otto C Boerman
Overview
Explore the profile of Otto C Boerman including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
319
Citations
7475
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Oosterwijk-Wakka J, de Weijert M, Franssen G, Kolev D, de Haan T, Boerman O, et al.
Neoplasia
. 2022 Jul;
32:100826.
PMID: 35878454
Sunitinib is an effective treatment for patients with metastatic Renal Cell Carcinoma (mRCC) but ultimately resistance occurs. The aim of this study was to investigate sunitinib resistance in RCCs and...
2.
de Gooyer J, Elekonawo F, Bremers A, Boerman O, Aarntzen E, de Reuver P, et al.
Nat Commun
. 2022 May;
13(1):2621.
PMID: 35551444
In patients with colorectal peritoneal metastases scheduled for cytoreductive surgery, accurate preoperative estimation of tumor burden and subsequent intraoperative detection of all tumor deposits remains challenging. In this study (ClinicalTrials.gov...
3.
van Lith S, Huizing F, Franssen G, Hoeben B, Lok J, Doulkeridou S, et al.
Mol Pharm
. 2022 Jan;
19(10):3511-3520.
PMID: 35044182
Hypoxic areas are present in the majority of solid tumors, and hypoxia is associated with resistance to therapies and poor outcomes. A transmembrane protein that is upregulated by tumor cells...
4.
Huizing F, Hoeben B, Lok J, Boerman O, Heskamp S, Bussink J
Phys Imaging Radiat Oncol
. 2021 Sep;
19:145-150.
PMID: 34485720
Background And Purpose: Tumor hypoxia is an important cause of radioresistance and is associated with poor outcome.SPECT (Single-photon emission computed tomography) imaging enables visualizing tumor characteristics. We investigated the SPECT-radiotracer...
5.
Waldhauer I, Gonzalez-Nicolini V, Freimoser-Grundschober A, Nayak T, Fahrni L, Hosse R, et al.
MAbs
. 2021 May;
13(1):1913791.
PMID: 33974508
Simlukafusp alfa (FAP-IL2v, RO6874281/RG7461) is an immunocytokine comprising an antibody against fibroblast activation protein α (FAP) and an IL-2 variant with a retained affinity for IL-2Rβγ > IL-2 Rβγ and...
6.
van Heijster F, Heskamp S, Breukels V, Veltien A, Franssen G, Jansen K, et al.
NMR Biomed
. 2020 Jul;
33(10):e4362.
PMID: 32662543
Reprogramming of energy metabolism in the development of prostate cancer can be exploited for a better diagnosis and treatment of the disease. The goal of this study was to determine...
7.
Elekonawo F, de Gooyer J, Bos D, Goldenberg D, Boerman O, Brosens L, et al.
Cancers (Basel)
. 2020 Apr;
12(4).
PMID: 32316388
Image-guided surgery can aid in achieving complete tumor resection. The development and assessment of tumor-targeted imaging probes for near-infrared fluorescence image-guided surgery relies mainly on preclinical models, but the translation...
8.
Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity
Nadar R, Farbod K, der Schilden K, Schlatt L, Crone B, Asokan N, et al.
Sci Rep
. 2020 Apr;
10(1):5889.
PMID: 32246003
Platinum-based chemotherapeutics exhibit excellent antitumor properties. However, these drugs cause severe side effects including toxicity, drug resistance, and lack of tumor selectivity. Tumor-targeted drug delivery has demonstrated great potential to...
9.
Elekonawo F, Bos D, Goldenberg D, Boerman O, Rijpkema M
EJNMMI Res
. 2019 Dec;
9(1):108.
PMID: 31828541
Background: In colorectal cancer, survival of patients is drastically reduced when complete resection is hampered by involvement of critical structures. Targeted photodynamic therapy (tPDT) is a local and targeted therapy...
10.
Huizing F, Garousi J, Lok J, Franssen G, Hoeben B, Frejd F, et al.
Sci Rep
. 2019 Dec;
9(1):18898.
PMID: 31827111
Hypoxia-induced carbonic anhydrase IX (CAIX) expression is a prognostic marker in solid tumors. In recent years many radiotracers have been developed, but a fair comparison of these compounds is not...