Ottavia M Delmonte
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Explore the profile of Ottavia M Delmonte including associated specialties, affiliations and a list of published articles.
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72
Citations
3280
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Recent Articles
11.
Momenilandi M, Levy R, Sobrino S, Li J, Lagresle-Peyrou C, Esmaeilzadeh H, et al.
Cell
. 2024 May;
187(11):2817-2837.e31.
PMID: 38701783
FMS-related tyrosine kinase 3 ligand (FLT3L), encoded by FLT3LG, is a hematopoietic factor essential for the development of natural killer (NK) cells, B cells, and dendritic cells (DCs) in mice....
12.
Materna M, Delmonte O, Bosticardo M, Momenilandi M, Conrey P, Charmeteau-De Muylder B, et al.
Science
. 2024 Feb;
383(6686):eadh4059.
PMID: 38422122
We describe humans with rare biallelic loss-of-function variants impairing pre-α T cell receptor (pre-TCRα) expression. Low circulating naive αβ T cell counts at birth persisted over time, with normal memory...
13.
Dinges S, Amini K, Notarangelo L, Delmonte O
Immunol Rev
. 2024 Jan;
322(1):178-211.
PMID: 38228406
The thymus is the primary site of T-cell development, enabling generation, and selection of a diverse repertoire of T cells that recognize non-self, whilst remaining tolerant to self- antigens. Severe...
14.
Matuozzo D, Talouarn E, Marchal A, Zhang P, Manry J, Seeleuthner Y, et al.
Genome Med
. 2024 Jan;
16(1):6.
PMID: 38184654
No abstract available.
15.
Delmonte O, Oguz C, Dobbs K, Myint-Hpu K, Palterer B, Abers M, et al.
J Allergy Clin Immunol
. 2023 Dec;
153(6):1655-1667.
PMID: 38154666
Background: Functional T-cell responses are essential for virus clearance and long-term protection after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, whereas certain clinical factors, such as older age and...
16.
Gazzin A, Pala F, Bosticardo M, Niemela J, Stoddard J, Biasin E, et al.
Front Immunol
. 2023 Dec;
14:1303251.
PMID: 38116000
Introduction: Mulibrey nanism (MUL) is a rare disorder caused by gene variants characterized by growth failure, dysmorphic features, congestive heart failure (CHF), and an increased risk of Wilms' tumor. Although...
17.
Pavel-Dinu M, Gardner C, Nakauchi Y, Kawai T, Delmonte O, Palterer B, et al.
Blood Adv
. 2023 Dec;
8(7):1820-1833.
PMID: 38096800
Recombination-activating genes (RAG1 and RAG2) are critical for lymphoid cell development and function by initiating the variable (V), diversity (D), and joining (J) (V(D)J)-recombination process to generate polyclonal lymphocytes with...
18.
Kuehn H, Sakovich I, Niemela J, Gil Silva A, Stoddard J, Polyakova E, et al.
J Clin Invest
. 2023 Nov;
134(3).
PMID: 38015619
AIOLOS, also known as IKZF3, is a transcription factor that is highly expressed in the lymphoid lineage and is critical for lymphocyte differentiation and development. Here, we report on 9...
19.
Le Voyer T, Parent A, Liu X, Cederholm A, Gervais A, Rosain J, et al.
Nature
. 2023 Nov;
623(7988):803-813.
PMID: 37938781
Patients with autoimmune polyendocrinopathy syndrome type 1 (APS-1) caused by autosomal recessive AIRE deficiency produce autoantibodies that neutralize type I interferons (IFNs), conferring a predisposition to life-threatening COVID-19 pneumonia. Here...
20.
Zendt M, Bustos Carrillo F, Kelly S, Saturday T, Degrange M, Ginigeme A, et al.
Sci Adv
. 2023 Oct;
9(41):eadh3150.
PMID: 37824621
Research on coronavirus disease 2019 vaccination in immune-deficient/disordered people (IDP) has focused on cancer and organ transplantation populations. In a prospective cohort of 195 IDP and 35 healthy volunteers (HV),...