Oshadhi T Jayasinghe
Overview
Explore the profile of Oshadhi T Jayasinghe including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
17
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Recent Articles
1.
Jayasinghe O, Ritchey L, Breil T, Newman P, Yakhnin H, Babitzke P
Nucleic Acids Res
. 2024 Nov;
52(21):12945-12960.
PMID: 39494516
Transcription by RNA polymerase is punctuated by transient pausing events. Pausing provides time for RNA folding and binding of regulatory factors to the paused elongation complex. We previously identified 1600...
2.
Mahendran G, Jayasinghe O, Thavakumaran D, Mirihana Arachchilage G, Silva G
Biochem Biophys Rep
. 2022 May;
30:101276.
PMID: 35592614
Precise regulation of gene expression is crucial for living cells to adapt for survival in diverse environmental conditions. Among the common cellular regulatory mechanisms, RNA-based regulators play a key role...
3.
Jayasinghe O, Mandell Z, Yakhnin A, Kashlev M, Babitzke P
J Bacteriol
. 2022 Mar;
204(5):e0053421.
PMID: 35258320
Transcription elongation is a highly processive process that is punctuated by RNA polymerase (RNAP) pausing. Long-lived pauses can provide time for diverse regulatory events to occur, which play important roles...