Orna Atar
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Explore the profile of Orna Atar including associated specialties, affiliations and a list of published articles.
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11
Citations
101
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Recent Articles
1.
Toledano Zur R, Atar O, Barliya T, Hoogi S, Abramovich I, Gottlieb E, et al.
J Immunother Cancer
. 2024 Jul;
12(7).
PMID: 38964783
Background: T cells play a central role in the antitumor response. However, they often face numerous hurdles in the tumor microenvironment, including the scarcity of available essential metabolites such as...
2.
Katz N, Tripto E, Granik N, Goldberg S, Atar O, Yakhini Z, et al.
Nat Commun
. 2021 Mar;
12(1):1576.
PMID: 33707432
We apply an oligo-library and machine learning-approach to characterize the sequence and structural determinants of binding of the phage coat proteins (CPs) of bacteriophages MS2 (MCP), PP7 (PCP), and Qβ...
3.
Anavy L, Vaknin I, Atar O, Amit R, Yakhini Z
Nat Biotechnol
. 2019 Sep;
37(10):1237.
PMID: 31527732
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
4.
Anavy L, Vaknin I, Atar O, Amit R, Yakhini Z
Nat Biotechnol
. 2019 Sep;
37(10):1229-1236.
PMID: 31501560
The density and long-term stability of DNA make it an appealing storage medium, particularly for long-term data archiving. Existing DNA storage technologies involve the synthesis and sequencing of multiple nominally...
5.
Katz N, Cohen R, Atar O, Goldberg S, Amit R
J Vis Exp
. 2019 Jul;
(148).
PMID: 31259904
In the initiation step of protein translation, the ribosome binds to the initiation region of the mRNA. Translation initiation can be blocked by binding of an RNA binding protein (RBP)...
6.
Katz N, Cohen R, Solomon O, Kaufmann B, Atar O, Yakhini Z, et al.
Cell Syst
. 2019 May;
9(1):93-106.e8.
PMID: 31129060
The construction of complex gene-regulatory networks requires both inhibitory and upregulatory modules. However, the vast majority of RNA-based regulatory "parts" are inhibitory. Using a synthetic biology approach combined with SHAPE-seq,...
7.
Katz N, Cohen R, Solomon O, Kaufmann B, Atar O, Yakhini Z, et al.
ACS Synth Biol
. 2018 Nov;
7(12):2765-2774.
PMID: 30408420
We study translation repression in bacteria by engineering a regulatory circuit that functions as a binding assay for RNA binding proteins (RBP) in vivo. We do so by inducing expression...
8.
Levy L, Anavy L, Solomon O, Cohen R, Brunwasser-Meirom M, Ohayon S, et al.
Cell Rep
. 2017 Oct;
21(3):845-858.
PMID: 29045849
We use an oligonucleotide library of >10,000 variants to identify an insulation mechanism encoded within a subset of σ promoters. Insulation manifests itself as reduced protein expression for a downstream...
9.
Brunwasser-Meirom M, Pollak Y, Goldberg S, Levy L, Atar O, Amit R
Nat Commun
. 2016 Feb;
7:10407.
PMID: 26832446
We explore a model for 'quenching-like' repression by studying synthetic bacterial enhancers, each characterized by a different binding site architecture. To do so, we take a three-pronged approach: first, we...
10.
Atar O, Avraham K
Drug Discov Today
. 2005 Oct;
10(19):1323-30.
PMID: 16214677
With the completion of the sequencing of the human genome, the field of medicine is undergoing a dramatic and fundamental change. The identification of our genes and the proteins they...