Orn Almarsson
Overview
Explore the profile of Orn Almarsson including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
30
Citations
1907
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Burdette D, Ci L, Shilliday B, Slauter R, Auerbach A, Kenney M, et al.
Drug Metab Dispos
. 2023 May;
51(7):804-812.
PMID: 37208185
The emerging therapeutic modality of lipid nanoparticle (LNP)-encapsulated mRNAs has demonstrated promising clinical results when used as vaccines and is currently being tested in formulations for a wide range of...
2.
Ci L, Hard M, Zhang H, Gandham S, Hua S, Wickwire J, et al.
Drug Metab Dispos
. 2023 May;
51(7):813-823.
PMID: 37208184
RNA-based therapeutics and vaccines represent a novel and expanding class of medicines, the success of which depends on the encapsulation and protection of mRNA molecules in lipid nanoparticle (LNP)-based carriers....
3.
Oude Blenke E, Ornskov E, Schoneich C, Nilsson G, Volkin D, Mastrobattista E, et al.
J Pharm Sci
. 2022 Nov;
112(2):386-403.
PMID: 36351479
The remarkable impact of mRNA vaccines on mitigating disease and improving public health has been amply demonstrated during the COVID-19 pandemic. Many new mRNA-based vaccine and therapeutic candidates are in...
4.
Bahl K, Senn J, Yuzhakov O, Bulychev A, Brito L, Hassett K, et al.
Mol Ther
. 2022 Aug;
30(8):2874.
PMID: 35921837
No abstract available.
5.
Hassett K, Higgins J, Woods A, Levy B, Xia Y, Hsiao C, et al.
J Control Release
. 2021 May;
335:237-246.
PMID: 34019945
Lipid nanoparticles (LNP) are effective delivery vehicles for messenger RNA (mRNA) and have shown promise for vaccine applications. Yet there are no published reports detailing how LNP biophysical properties can...
6.
Patel S, Ashwanikumar N, Robinson E, Xia Y, Mihai C, Griffith 3rd J, et al.
Nat Commun
. 2020 Jul;
11(1):3435.
PMID: 32632117
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
7.
Patel S, Ashwanikumar N, Robinson E, Xia Y, Mihai C, Griffith 3rd J, et al.
Nat Commun
. 2020 Feb;
11(1):983.
PMID: 32080183
Endosomal sequestration of lipid-based nanoparticles (LNPs) remains a formidable barrier to delivery. Herein, structure-activity analysis of cholesterol analogues reveals that incorporation of C-24 alkyl phytosterols into LNPs (eLNPs) enhances gene...
8.
Hassett K, Benenato K, Jacquinet E, Lee A, Woods A, Yuzhakov O, et al.
Mol Ther Nucleic Acids
. 2019 Feb;
15:1-11.
PMID: 30785039
mRNA vaccines have the potential to tackle many unmet medical needs that are unable to be addressed with conventional vaccine technologies. A potent and well-tolerated delivery technology is integral to...
9.
Sabnis S, Kumarasinghe E, Salerno T, Mihai C, Ketova T, Senn J, et al.
Mol Ther
. 2018 Apr;
26(6):1509-1519.
PMID: 29653760
The success of mRNA-based therapies depends on the availability of a safe and efficient delivery vehicle. Lipid nanoparticles have been identified as a viable option. However, there are concerns whether...
10.
Patel S, Ashwanikumar N, Robinson E, DuRoss A, Sun C, Murphy-Benenato K, et al.
Nano Lett
. 2017 Aug;
17(9):5711-5718.
PMID: 28836442
Intracellular delivery of mRNA holds great potential for vaccine1-3 and therapeutic4 discovery and development. Despite increasing recognition of the utility of lipid-based nanoparticles (LNPs) for intracellular delivery of mRNA, particle...