Onur Cil
Overview
Explore the profile of Onur Cil including associated specialties, affiliations and a list of published articles.
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Articles
49
Citations
400
Followers
0
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Recent Articles
1.
Touhara K, Rossen N, Deng F, Castro J, Harrington A, Chu T, et al.
Nature
. 2025 Feb;
PMID: 39939779
The crypt-villus structure of the small intestine serves as an essential protective barrier. The integrity of this barrier is monitored by the complex sensory system of the gut, in which...
2.
Master R, Karmakar J, Haggie P, Anthony-Tan J, Chu T, Verkman A, et al.
Eur J Med Chem
. 2024 Dec;
283:117133.
PMID: 39642691
Pendrin (SLC26A4) is an anion exchanger expressed in epithelial cells of kidney and lung. Pendrin inhibition is a potential treatment approach for edema, hypertension and inflammatory lung diseases. We have...
3.
Gao Q, Cil O
Trends Pharmacol Sci
. 2024 Jul;
45(8):708-722.
PMID: 39019764
Magnesium (Mg) is a commonly used dietary supplement for the prevention and treatment of diseases. However, the efficacy and mechanisms of action of Mg in most diseases have been controversial...
4.
Pasricha N, Lindgren E, Yan R, Kuo Y, Chan M, Verkman A, et al.
Ocul Surf
. 2024 Jun;
34:30-37.
PMID: 38871216
Purpose: Ocular surface hydration is critical for eye health and its impairment can lead to dry eye disease. Extracellular calcium-sensing receptor (CaSR) is regulator of ion transport in epithelial cells...
5.
Sarthi J, Trumbull A, Abazari S, van Unen V, Chan J, Jiang Y, et al.
JCI Insight
. 2024 Jun;
9(14).
PMID: 38869953
Duodenal bicarbonate secretion is critical to epithelial protection, as well as nutrient digestion and absorption, and is impaired in cystic fibrosis (CF). We examined if linaclotide, typically used to treat...
6.
Ahmadi M, de Souza Goncalves L, Verkman A, Cil O, Anderson M
RSC Med Chem
. 2024 May;
15(5):1731-1736.
PMID: 38784456
SLC26A3, also known as downregulated in adenoma (DRA), is an anion (Cl, HCO and oxalate) exchanger in the luminal membrane of intestinal epithelial cells. Loss of DRA function in mice...
7.
Lindgren E, Yan R, Cil O, Verkman A, Chan M, Seitzman G, et al.
Curr Ophthalmol Rep
. 2024 May;
12(2):13-22.
PMID: 38756824
Purpose Of Review: This study is to highlight the incidence of corneal pseudomicrocysts in FDA-approved antibody-drug conjugates (ADCs), and success of preventive therapies for pseudomicrocysts and related ocular surface adverse...
8.
Touhara K, Rossen N, Deng F, Chu T, Harrington A, Garcia Caraballo S, et al.
bioRxiv
. 2024 Feb;
PMID: 38370814
The crypt-villus structure of the small intestine serves as an essential protective barrier, with its integrity monitored by the gut's sensory system. Enterochromaffin (EC) cells, which are rare sensory epithelial...
9.
Lindgren E, Cil O, Verkman A, Pasricha N
Curr Ophthalmol Rep
. 2024 Jan;
10(4):188-197.
PMID: 38213468
Purpose Of Review: To review the role of ocular surface epithelial (corneal and conjunctival) ion transporters in the pathogenesis and treatment of dry eye disease (DED). Recent Findings: Currently, anti-inflammatory...
10.
Yottasan P, Chu T, Chhetri P, Cil O
Transl Res
. 2023 Nov;
265:17-25.
PMID: 37990828
ADPKD is characterized by progressive cyst formation and enlargement leading to kidney failure. Tolvaptan is currently the only FDA-approved treatment for ADPKD; however, it can cause serious adverse effects including...