Olivier Soubias
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Explore the profile of Olivier Soubias including associated specialties, affiliations and a list of published articles.
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35
Citations
762
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Recent Articles
1.
Soubias O, Foley S, Jian X, Jackson R, Zhang Y, Rosenberg E, et al.
bioRxiv
. 2025 Jan;
PMID: 39763923
ASAP1 is a multidomain Arf GTPase-activating protein (ArfGAP) that catalyzes GTP hydrolysis on the small GTPase Arf1 and is implicated in cancer progression. The PH domain of ASAP1 enhances its...
2.
Rosenberg Jr E, Jian X, Soubias O, Jackson R, Gladu E, Andersen E, et al.
PLoS One
. 2024 Apr;
19(4):e0295103.
PMID: 38574162
The ADP-ribosylation factors (Arfs) constitute a family of small GTPases within the Ras superfamily, with a distinguishing structural feature of a hypervariable N-terminal extension of the G domain modified with...
3.
Zhang Y, Soubias O, Pant S, Heinrich F, Vogel A, Li J, et al.
Nat Commun
. 2023 Nov;
14(1):7570.
PMID: 37989735
ADP-ribosylation factor 1 (Arf1) interacts with multiple cellular partners and membranes to regulate intracellular traffic, organelle structure and actin dynamics. Defining the dynamic conformational landscape of Arf1 in its active...
4.
Zimmerberg J, Soubias O, Pastor R
Biophys J
. 2023 Mar;
122(6):E1-E8.
PMID: 36921597
No abstract available.
5.
Rosenberg Jr E, Jian X, Soubias O, Yoon H, Yadav M, Hammoudeh S, et al.
J Biol Chem
. 2023 Feb;
299(3):102992.
PMID: 36758799
The ADP-ribosylation factor (Arf) GTPases and their regulatory proteins are implicated in cancer progression. NAV-2729 was previously identified as a specific inhibitor of Arf6 that reduced progression of uveal melanoma...
6.
Soubias O, Sodt A, Teague W, Hines K, Gawrisch K
Biophys J
. 2022 Nov;
122(6):973-983.
PMID: 36419350
We monitored the effect on function of the G-protein-coupled receptor (GPCR) rhodopsin from small, stepwise changes in bilayer thickness induced by cholesterol. Over a range of phosphatidylcholine bilayers with hydrophobic...
7.
8.
Soubias O, Pant S, Heinrich F, Zhang Y, Roy N, Li J, et al.
Sci Adv
. 2020 Oct;
6(40).
PMID: 32998886
Adenosine diphosphate-ribosylation factor (Arf) guanosine triphosphatase-activating proteins (GAPs) are enzymes that need to bind to membranes to catalyze the hydrolysis of guanosine triphosphate (GTP) bound to the small GTP-binding protein...
9.
Li J, Zhang Y, Soubias O, Khago D, Chao F, Li Y, et al.
J Biol Chem
. 2020 Jan;
295(9):2664-2675.
PMID: 31974162
Engineering and bioconjugation of proteins is a critically valuable tool that can facilitate a wide range of biophysical and structural studies. The ability to orthogonally tag or label a domain...
10.
Roy N, Jian X, Soubias O, Zhai P, Hall J, Dagher J, et al.
J Biol Chem
. 2019 Oct;
294(46):17354-17370.
PMID: 31591270
Arf GAP with Src homology 3 domain, ankyrin repeat, and pleckstrin homology (PH) domain 1 (ASAP1) is a multidomain GTPase-activating protein (GAP) for ADP-ribosylation factor (ARF)-type GTPases. ASAP1 affects integrin...