Olivier Lespinet
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Explore the profile of Olivier Lespinet including associated specialties, affiliations and a list of published articles.
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35
Citations
975
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Recent Articles
1.
Papadopoulos C, Arbes H, Cornu D, Chevrollier N, Blanchet S, Roginski P, et al.
Genome Biol
. 2024 Oct;
25(1):268.
PMID: 39402662
Background: Pervasive translation is a widespread phenomenon that plays a critical role in the emergence of novel microproteins, but the diversity of translation patterns contributing to their generation remains unclear....
2.
Haas D, Barba M, Vicente C, Nezbedova S, Garenaux A, Bury-Mone S, et al.
NAR Genom Bioinform
. 2024 Jun;
6(2):lqae069.
PMID: 38915823
Microbial specialized metabolite biosynthetic gene clusters (SMBGCs) are a formidable source of natural products of pharmaceutical interest. With the multiplication of genomic data available, very efficient bioinformatic tools for automatic...
3.
Oliveira L, Chevrollier N, Dallery J, OConnell R, Lebrun M, Viaud M, et al.
Sci Rep
. 2023 Jan;
13(1):1417.
PMID: 36697464
We report here a new application, CustomProteinSearch (CusProSe), whose purpose is to help users to search for proteins of interest based on their domain composition. The application is customizable. It...
4.
Bastide P, Soneson C, Stern D, Lespinet O, Gallopin M
Mol Biol Evol
. 2022 Dec;
40(1).
PMID: 36508357
Interspecies RNA-Seq datasets are increasingly common, and have the potential to answer new questions about the evolution of gene expression. Single-species differential expression analysis is now a well-studied problem that...
5.
Gianfrotta C, Reinharz V, Lespinet O, Barth D, Denise A
RNA Biol
. 2022 Nov;
19(1):1208-1227.
PMID: 36384383
This study investigates the importance of the structural context in the formation of a type I/II A-minor motif. This very frequent structural motif has been shown to be important in...
6.
Papadopoulos C, Callebaut I, Gelly J, Hatin I, Namy O, Renard M, et al.
Genome Res
. 2021 Nov;
31(12):2303-2315.
PMID: 34810219
The noncoding genome plays an important role in de novo gene birth and in the emergence of genetic novelty. Nevertheless, how noncoding sequences' properties could promote the birth of novel...
7.
Lioy V, Lorenzi J, Najah S, Poinsignon T, Leh H, Saulnier C, et al.
Nat Commun
. 2021 Sep;
12(1):5221.
PMID: 34471117
Bacteria of the genus Streptomyces are prolific producers of specialized metabolites, including antibiotics. The linear chromosome includes a central region harboring core genes, as well as extremities enriched in specialized...
8.
Lorenzi J, Lespinet O, Leblond P, Thibessard A
Microb Genom
. 2021 Mar;
7(6).
PMID: 33749576
possess a large linear chromosome (6-12 Mb) consisting of a conserved central region flanked by variable arms covering several megabases. In order to study the evolution of the chromosome across...
9.
Tidjani A, Lorenzi J, Toussaint M, van Dijk E, Naquin D, Lespinet O, et al.
Microbiol Resour Announc
. 2019 Sep;
8(38).
PMID: 31537669
The genomes of 11 conspecific strains, i.e., from the same species and inhabiting the same ecological niche, were sequenced and assembled. This data set offers an ideal framework to assess...
10.
Tidjani A, Lorenzi J, Toussaint M, van Dijk E, Naquin D, Lespinet O, et al.
mBio
. 2019 Sep;
10(5).
PMID: 31481382
In this work, by comparing genomes of closely related individuals of isolated at a spatial microscale (millimeters or centimeters), we investigated the extent and impact of horizontal gene transfer in...