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Annabelle Thibessard

Explore the profile of Annabelle Thibessard including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 350
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Recent Articles
1.
Haas D, Barba M, Vicente C, Nezbedova S, Garenaux A, Bury-Mone S, et al.
NAR Genom Bioinform . 2024 Jun; 6(2):lqae069. PMID: 38915823
Microbial specialized metabolite biosynthetic gene clusters (SMBGCs) are a formidable source of natural products of pharmaceutical interest. With the multiplication of genomic data available, very efficient bioinformatic tools for automatic...
2.
Dagva O, Thibessard A, Lorenzi J, Labat V, Piotrowski E, Rouhier N, et al.
Nucleic Acids Res . 2024 Mar; 52(9):5033-5047. PMID: 38444149
The linear chromosome of Streptomyces exhibits a highly compartmentalized structure with a conserved central region flanked by variable arms. As double strand break (DSB) repair mechanisms play a crucial role...
3.
Bury-Mone S, Thibessard A, Lioy V, Leblond P
Trends Genet . 2023 Sep; 39(11):873-887. PMID: 37679290
Streptomyces are prolific producers of specialized metabolites with applications in medicine and agriculture. Remarkably, these bacteria possess a large linear chromosome that is genetically compartmentalized: core genes are grouped in...
4.
Dulermo T, Lejeune C, Aybeke E, Abreu S, Bleton J, David M, et al.
Microorganisms . 2023 Jun; 11(6). PMID: 37374972
M145 is a model strain extensively studied to elucidate the regulation of antibiotic biosynthesis in species. This strain abundantly produces the blue polyketide antibiotic, actinorhodin (ACT), and has a low...
5.
Lorenzi J, Thibessard A, Lioy V, Boccard F, Leblond P, Pernodet J, et al.
Nucleic Acids Res . 2022 Nov; 50(20):11654-11669. PMID: 36408918
Streptomyces are prolific producers of specialized metabolites with applications in medicine and agriculture. These bacteria possess a large linear chromosome genetically compartmentalized: core genes are grouped in the central part,...
6.
Lioy V, Lorenzi J, Najah S, Poinsignon T, Leh H, Saulnier C, et al.
Nat Commun . 2021 Sep; 12(1):5221. PMID: 34471117
Bacteria of the genus Streptomyces are prolific producers of specialized metabolites, including antibiotics. The linear chromosome includes a central region harboring core genes, as well as extremities enriched in specialized...
7.
Lorenzi J, Lespinet O, Leblond P, Thibessard A
Microb Genom . 2021 Mar; 7(6). PMID: 33749576
possess a large linear chromosome (6-12 Mb) consisting of a conserved central region flanked by variable arms covering several megabases. In order to study the evolution of the chromosome across...
8.
David M, Lejeune C, Abreu S, Thibessard A, Leblond P, Chaminade P, et al.
Antibiotics (Basel) . 2020 May; 9(6). PMID: 32466356
Streptomycetes are well known antibiotic producers and are among the rare prokaryotes able to store carbon as lipids. Previous comparative studies of the weak antibiotic producer with its mutant and...
9.
Bertrand C, Thibessard A, Bruand C, Lecointe F, Leblond P
Mol Microbiol . 2019 Feb; 111(5):1139-1151. PMID: 30746801
Double-strand breaks (DSBs) are the most detrimental DNA damage encountered by bacterial cells. DBSs can be repaired by homologous recombination thanks to the availability of an intact DNA template or...
10.
Thibessard A, Vicente C, Bertrand C, Aigle B, Leblond P
Microbiol Resour Announc . 2018 Dec; 7(12). PMID: 30533680
The draft genome of Streptomyces sp. strain ETH9427 was sequenced and assembled into three large scaffolds, a 7.745-Mb linear chromosome with terminal inverted repeats of 201 kb and two probable...