Olivier Dumortier
Overview
Explore the profile of Olivier Dumortier including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
291
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0
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Recent Articles
1.
Dumortier O, Fabris G, Pisani D, Casamento V, Gautier N, Hinault C, et al.
J Endocrinol
. 2019 Nov;
244(1):189-200.
PMID: 31697642
Enhanced beta cell glycolytic and oxidative metabolism are necessary for glucose-induced insulin secretion. While several microRNAs modulate beta cell homeostasis, miR-375 stands out as it is highly expressed in beta...
2.
Fabris G, Dumortier O, Pisani D, Gautier N, Van Obberghen E
Cell Death Dis
. 2019 Jul;
10(8):566.
PMID: 31332188
In an adult healthy liver, hepatocytes are in a quiescent stage unless a physical injury, such as ablation, or a toxic attack occur. Indeed, to maintain their crucial organismal homeostatic...
3.
Roger E, Dumortier O, Pisani D, Gautier N, Van Obberghen E, Hinault C
Biochim Biophys Acta Mol Basis Dis
. 2019 Jun;
1865(9):2393-2402.
PMID: 31152866
MicroRNAs (miRNAs) are important modulators of thermogenic brown adipose tissue (BAT). They have been involved in its differentiation and hence its functioning. While different regulators of the miRNA machinery have...
4.
Sanchez-Parra C, Jacovetti C, Dumortier O, Lee K, Peyot M, Guay C, et al.
Diabetes
. 2018 Aug;
67(11):2254-2267.
PMID: 30115652
Pancreatic β-cell expansion throughout the neonatal period is essential to generate the appropriate mass of insulin-secreting cells required to maintain blood glucose homeostasis later in life. Hence, defects in this...
5.
Dumortier O, Roger E, Pisani D, Casamento V, Gautier N, Lebrun P, et al.
Diabetes
. 2016 Dec;
66(3):627-639.
PMID: 27927722
Epidemiological and animal studies show that deleterious maternal environments predispose aging offspring to metabolic disorders and type 2 diabetes. Young progenies in a rat model of maternal low-protein (LP) diet...
6.
Attane C, Peyot M, Lussier R, Poursharifi P, Zhao S, Zhang D, et al.
Diabetologia
. 2016 Sep;
59(12):2654-2663.
PMID: 27677764
Aims/hypothesis: To directly assess the role of beta cell lipolysis in insulin secretion and whole-body energy homeostasis, inducible beta cell-specific adipose triglyceride lipase (ATGL)-deficient (B-Atgl-KO) mice were studied under normal...
7.
Pisani D, Dumortier O, Beranger G, Casamento V, Ghandour R, Giroud M, et al.
Adipocyte
. 2016 Jul;
5(2):186-95.
PMID: 27386154
Human brown adipocytes are able to burn fat and glucose and are now considered as a potential strategy to treat obesity, type 2 diabetes and metabolic disorders. Besides their thermogenic...
8.
Raffort J, Hinault C, Dumortier O, Van Obberghen E
Diabetologia
. 2015 Jul;
58(9):1978-92.
PMID: 26155747
The explosive increase in the worldwide prevalence of diabetes over recent years has transformed the disease into a major public health concern. While diabetes can be screened for and diagnosed...
9.
Dumortier O, Hinault C, Gautier N, Patouraux S, Casamento V, Van Obberghen E
Diabetes
. 2014 May;
63(10):3416-27.
PMID: 24834976
The intrauterine environment of the fetus is a preeminent actor in long-term health. Indeed, mounting evidence shows that maternal malnutrition increases the risk of type 2 diabetes (T2D) in progeny....
10.
Hinault C, Dumortier O, Van Obberghen E
Med Sci (Paris)
. 2013 Sep;
29(8-9):785-90.
PMID: 24005635
Soon after their discovery microRNA (miRNA) emerged as central natural regulators of gene expression. Although the complex mechanisms of action and impact of miRNA on development, physiology and disease are...