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Marc Prentki

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Articles 115
Citations 8079
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Recent Articles
1.
Lau D, Tobin S, Pribiag H, Nakajima S, Fisette A, Matthys D, et al.
Nat Commun . 2024 Dec; 15(1):10652. PMID: 39681558
α/β-hydrolase domain 6 (ABHD6) is a lipase linked to physiological functions affecting energy metabolism. Brain ABHD6 degrades 2-arachidonoylglycerol and thereby modifies cannabinoid receptor signalling. However, its functional role within mesoaccumbens...
2.
Ghosh A, Chenier I, Leung Y, Oppong A, Peyot M, Murthy Madiraju S, et al.
iScience . 2024 Dec; 27(12):111292. PMID: 39640567
Angiopoietin-like protein 8 (Angptl8), expressed in the liver and adipocytes, forms a complex with Angptl3 or Angptl4, which regulates lipoprotein lipase and triglyceride metabolism. However, the precise functions of adipocyte...
3.
Oppong A, Leung Y, Ghosh A, Peyot M, Paquet M, Morales C, et al.
Mol Metab . 2024 Nov; 90:102063. PMID: 39542419
Objectives: Obesity, diabetes and high-calorie diets are associated with defective sperm function and lowered male fertility. Mature spermatozoa primarily use fructose and glucose, and glucose and glycerol metabolism are important...
4.
Sun C, Nguyen E, Prentki M, Rabasa-Lhoret R
Diabetes Obes Metab . 2024 Jun; 26(8):3486-3488. PMID: 38840460
No abstract available.
5.
Xu T, Yin J, Dai X, Liu T, Shi H, Zhang Y, et al.
Phytomedicine . 2024 Mar; 128:155375. PMID: 38507853
Background: Osteoporosis (OP) is a prevalent chronic metabolic bone disease for which limited countermeasures are available. Cnidii Fructus (CF), primarily derived from Cnidium monnieri (L.) Cusson., has been tested in...
6.
Ghosh A, Leung Y, Yu J, Sladek R, Chenier I, Oppong A, et al.
Biochim Biophys Acta Mol Cell Biol Lipids . 2024 Jan; 1869(3):159461. PMID: 38272177
ANGPTL8, expressed mainly in the liver and adipose tissue, regulates the activity of lipoprotein lipase (LPL) present in the extracellular space and triglyceride (TG) metabolism through its interaction with ANGPTL3...
7.
Dai X, Liu Y, Liu T, Zhang Y, Wang S, Xu T, et al.
J Ethnopharmacol . 2023 Sep; 319(Pt 2):117167. PMID: 37716489
Ethnopharmacological Relevance: SiJunZi decoction (SJZD), one of the traditional Chinese medicine formulas, has been clinically and traditionally used to improve glucose and lipid metabolism and promote bone remodeling. Aim Of...
8.
Possik E, Klein L, Sanjab P, Zhu R, Cote L, Bai Y, et al.
Nat Commun . 2023 Aug; 14(1):5214. PMID: 37626039
Metabolic stress caused by excess nutrients accelerates aging. We recently demonstrated that the newly discovered enzyme glycerol-3-phosphate phosphatase (G3PP; gene Pgp), which operates an evolutionarily conserved glycerol shunt that hydrolyzes...
9.
Ghosh A, Peyot M, Leung Y, Ravenelle F, Murthy Madiraju S, Prentki M
Eur J Pharmacol . 2023 Feb; 944:175589. PMID: 36773683
The cannabinoid receptor CB1R is expressed in pancreatic β-cells; CB1R increased activity is associated with diabetes, obesity, cardiovascular disorders as well as decreased insulin secretion and insulin resistance. CB1R was...
10.
Al-Mass A, Poursharifi P, Peyot M, Lussier R, Chenier I, Leung Y, et al.
Mol Metab . 2022 Oct; 66:101609. PMID: 36198384
Objective: Glycerol-3-phosphate (Gro3P) phosphatase (G3PP) hydrolyzes Gro3P to glycerol that exits the cell, thereby operating a "glycerol shunt", a metabolic pathway that we identified recently in mammalian cells. We have...