Olga Volpert
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Explore the profile of Olga Volpert including associated specialties, affiliations and a list of published articles.
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14
Citations
397
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Recent Articles
1.
Kalia V, Jackson G, Dominguez R, Pinto-Pacheco B, Bloomquist T, Furnari J, et al.
medRxiv
. 2025 Feb;
PMID: 39974146
Extracellular vesicles (EVs) released by neurons (nEVs) provide an opportunity to measure biomarkers from the brain circulating in the periphery. No study yet has directly compared molecular cargo in brain...
2.
Tordoff E, Allen J, Elgart K, Elsherbini A, Kalia V, Wu H, et al.
J Extracell Vesicles
. 2024 Nov;
13(11):e70007.
PMID: 39498678
Small membranous extracellular vesicles (EV) incorporate proteins and nucleic acids from the parent cell. Proteins exposed on EV surface are dictated by cellular origin and biogenesis pathway. To better understand...
3.
Nogueras-Ortiz C, Eren E, Yao P, Calzada E, Dunn C, Volpert O, et al.
J Extracell Vesicles
. 2024 Jun;
13(6):e12459.
PMID: 38868956
Isolation of neuron-derived extracellular vesicles (NDEVs) with L1 Cell Adhesion Molecule (L1CAM)-specific antibodies has been widely used to identify blood biomarkers of CNS disorders. However, full methodological validation requires demonstration...
4.
Eitan E, Thornton-Wells T, Elgart K, Erden E, Gershun E, Levine A, et al.
Extracell Vesicles Circ Nucl Acids
. 2023 Oct;
4(1):133-150.
PMID: 37842184
Aims: Blood biomarkers can improve drug development for Alzheimer's disease (AD) and its treatment. Neuron-derived extracellular vesicles (NDEVs) in plasma offer a minimally invasive platform for developing novel biomarkers that...
5.
Delgado-Peraza F, Nogueras-Ortiz C, Volpert O, Liu D, Goetzl E, Mattson M, et al.
Cells
. 2021 Apr;
10(5).
PMID: 33922642
Circulating neuronal extracellular vesicles (NEVs) of Alzheimer's disease (AD) patients show high Tau and β-amyloid (Aβ) levels, whereas their astrocytic EVs (AEVs) contain high complement levels. To validate EV proteins...
6.
Michael I, Orebrand M, Lima M, Pereira B, Volpert O, Quaggin S, et al.
BMC Cancer
. 2017 Aug;
17(1):539.
PMID: 28800750
Background: Angipoietin-1 activation of the tyrosine kinase receptor Tek expressed mainly on endothelial cells leads to survival and stabilization of endothelial cells. Studies have shown that Angiopoietin-1 counteracts permeability induced...
7.
Park J, Peng H, Yang W, Katsnelson J, Volpert O, Lavker R
FASEB J
. 2016 Nov;
31(1):256-265.
PMID: 27825105
Corneal avascularity is critical for achieving transparency necessary for proper transmission of light to the lens and visual acuity. Although much is known about angiogenesis and angiostasis, the precise regulation...
8.
Plebanek M, Mutharasan R, Volpert O, Matov A, Gatlin J, Thaxton C
Sci Rep
. 2015 Oct;
5:15724.
PMID: 26511855
Exosomes are nanoscale vesicles that mediate intercellular communication. Cellular exosome uptake mechanisms are not well defined partly due to the lack of specific inhibitors of this complex cellular process. Exosome...
9.
McMahon K, Mutharasan R, Tripathy S, Veliceasa D, Bobeica M, Shumaker D, et al.
Nano Lett
. 2011 Feb;
11(3):1208-14.
PMID: 21319839
We report a gold nanoparticle-templated high density lipoprotein (HDL AuNP) platform for gene therapy that combines lipid-based nucleic acid transfection strategies with HDL biomimicry. For proof-of-concept, HDL AuNPs are shown...
10.
Xiao W, Ai J, Habermacher G, Volpert O, Yang X, Zhang A, et al.
Cancer Res
. 2009 Mar;
69(6):2599-606.
PMID: 19258512
Studies have firmly established a key regulatory role for the tumor suppressor pVHL in the regulation of the vascular system and normal spermatogenesis. Here, we report that knockout of the...