Edward J Goetzl
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Explore the profile of Edward J Goetzl including associated specialties, affiliations and a list of published articles.
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119
Citations
5182
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Recent Articles
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Goetzl E
Am J Med
. 2024 Dec;
PMID: 39631640
Recent applications of artificial intelligence-derived methods of computational design have permitted de novo creation of proteins that do not exist in nature but have potent effects on human cells and...
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Goetzl E
Am J Med
. 2024 Aug;
138(1):15-20.
PMID: 39197720
An increased understanding of the predisposing genetics and complex pathogenic mechanisms of Alzheimer's disease have facilitated delineation of the long preclinical course and re-invigorated the search for disease-modifying treatments. Establishment...
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Shroff R, Goetzl E
Am J Med
. 2024 Jun;
137(11):1055-1058.
PMID: 38925498
Cellular protein kinases are involved in diverse normal cellular functions. Many types of dysregulation of protein kinases are the molecular basis for development of common cancers and neurodegenerative diseases. More...
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Nogueras-Ortiz C, Eren E, Yao P, Calzada E, Dunn C, Volpert O, et al.
J Extracell Vesicles
. 2024 Jun;
13(6):e12459.
PMID: 38868956
Isolation of neuron-derived extracellular vesicles (NDEVs) with L1 Cell Adhesion Molecule (L1CAM)-specific antibodies has been widely used to identify blood biomarkers of CNS disorders. However, full methodological validation requires demonstration...
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Goetzl E, Alpert J, Chen Q
Am J Med
. 2024 May;
137(9):805-809.
PMID: 38795938
Modern medicine now has the capacity to improve therapy for many human diseases by introducing adult somatic stem cells that can repair or replace defective or damaged tissues. However, the...
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Goetzl E
FASEB J
. 2024 Feb;
38(4):e23485.
PMID: 38372961
Type 2 helper cells (Th2 cells) differentiate from CD4 helper T cells under the influence of IL-4 and conventional or monocyte-derived CD11b dendritic cells. Th2 cells are capable of generating...
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Delgado-Peraza F, Nogueras-Ortiz C, Simonsen A, Knight D, Yao P, Goetzl E, et al.
Alzheimers Res Ther
. 2024 Jan;
16(1):18.
PMID: 38263287
No abstract available.