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Olga A Tarasova

Explore the profile of Olga A Tarasova including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 50
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Recent Articles
1.
Ivanov S, Lagunin A, Tarasova O
Comput Struct Biotechnol J . 2025 Feb; 23:3559-3574. PMID: 39963421
Glioblastoma (GBM) is the most common malignant brain tumor with poor overall survival. Current treatment management for GBM has low efficacy, mainly due to high inter-patient heterogeneity. The transcription profiles...
2.
Biziukova N, Rudik A, Dmitriev A, Tarasova O, Filimonov D, Poroikov V
ACS Omega . 2025 Feb; 10(3):2459-2471. PMID: 39895765
Understanding the biotransformation of xenobiotics in the human body is critical for a comprehensive assessment of drug effects since pharmacologically active drug metabolites may exhibit a range of biological effects...
3.
Stolbova E, Stolbov L, Filimonov D, Poroikov V, Tarasova O
Viruses . 2024 Jul; 16(7). PMID: 39066293
Drug resistance of pathogens, including viruses, is one of the reasons for decreased efficacy of therapy. Considering the impact of HIV type 1 (HIV-1) on the development of progressive immune...
4.
Nedolya N, Tarasova O, Albanov A, Klyba L, Trofimov B
J Org Chem . 2023 Dec; 89(2):864-881. PMID: 38154056
Self-assembly of 4,4'-linked dipyrromethanes from 2-(vinyloxy)ethyl isothiocyanate, tertiary propargylamines, and alkylating agents has been discovered. The plausible reaction mechanism, the major stages of which have been confirmed experimentally, includes (1)...
5.
Paremskaia A, Rudik A, Filimonov D, Lagunin A, Poroikov V, Tarasova O
Viruses . 2023 Nov; 15(11). PMID: 38005921
Predicting viral drug resistance is a significant medical concern. The importance of this problem stimulates the continuous development of experimental and new computational approaches. The use of computational approaches allows...
6.
Tarasova O
Int J Mol Sci . 2023 Oct; 24(19). PMID: 37833992
Studies on virus-host interactions are of high significance for a number of reasons [...].
7.
Ivanov S, Tarasova O, Poroikov V
Front Immunol . 2023 Oct; 14:1199482. PMID: 37795081
Introduction: There are difficulties in creating direct antiviral drugs for all viruses, including new, suddenly arising infections, such as COVID-19. Therefore, pathogenesis-directed therapy is often necessary to treat severe viral...
8.
Artemev A, Doronina E, Rakhmanova M, Hei X, Stass D, Tarasova O, et al.
Dalton Trans . 2023 Mar; 52(13):4017-4027. PMID: 36880169
Exploiting 2-(alkylsulfonyl)pyridines as 1,3-N,S-ligands, herein we have constructed 1D CuI-based coordination polymers (CPs) bearing unprecedented (CuI) chains and possessing remarkable photophysical properties. At room temperature, these CPs show efficient TADF,...
9.
Lagunin A, Rudik A, Pogodin P, Savosina P, Tarasova O, Dmitriev A, et al.
Int J Mol Sci . 2023 Jan; 24(2). PMID: 36675202
In vitro cell-line cytotoxicity is widely used in the experimental studies of potential antineoplastic agents and evaluation of safety in drug discovery. In silico estimation of cytotoxicity against hundreds of...
10.
Tarasova O, Biziukova N, Rudik A, Dmitriev A, Filimonov D, Poroikov V
J Chem Inf Model . 2021 Mar; 61(4):1683-1690. PMID: 33724829
The growing amount of experimental data on chemical objects includes properties of small molecules, results of studies of their interaction with human and animal proteins, and methods of synthesis of...