Olga A Agapova
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Explore the profile of Olga A Agapova including associated specialties, affiliations and a list of published articles.
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16
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613
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Recent Articles
1.
Williams M, Sugatani T, Agapova O, Fang Y, Gaut J, Faugere M, et al.
Kidney Int
. 2017 Aug;
93(1):147-158.
PMID: 28843411
We examined activin receptor type IIA (ActRIIA) activation in chronic kidney disease (CKD) by signal analysis and inhibition in mice with Alport syndrome using the ActRIIA ligand trap RAP-011 initiated...
2.
Sugatani T, Agapova O, Fang Y, Berman A, Wallace J, Malluche H, et al.
Kidney Int
. 2016 Sep;
91(1):86-95.
PMID: 27666759
Dysregulation of skeletal remodeling is a component of renal osteodystrophy. Previously, we showed that activin receptor signaling is differentially affected in various tissues in chronic kidney disease (CKD). We tested...
3.
Agapova O, Fang Y, Sugatani T, Seifert M, Hruska K
Kidney Int
. 2016 May;
89(6):1231-43.
PMID: 27165838
The causes of cardiovascular mortality associated with chronic kidney disease (CKD) are partly attributed to the CKD-mineral bone disorder (CKD-MBD). The causes of the early CKD-MBD are not well known....
4.
Fu M, Landreville S, Agapova O, Wiley L, Shoykhet M, Harbour J, et al.
J Clin Invest
. 2013 Nov;
123(12):5152-64.
PMID: 24177421
The retinoblastoma 1 (RB1) tumor suppressor is a critical regulator of cell cycle progression and development. To investigate the role of RB1 in neural crest-derived melanocytes, we bred mice with...
5.
Matatall K, Agapova O, Onken M, Worley L, Bowcock A, Harbour J
BMC Cancer
. 2013 Aug;
13:371.
PMID: 23915344
Background: Uveal melanoma is a highly aggressive cancer with a strong propensity for metastasis, yet little is known about the biological mechanisms underlying this metastatic potential. We recently showed that...
6.
Landreville S, Agapova O, Matatall K, Kneass Z, Onken M, Lee R, et al.
Clin Cancer Res
. 2011 Nov;
18(2):408-16.
PMID: 22038994
Purpose: Metastasis is responsible for the death of most cancer patients, yet few therapeutic agents are available which specifically target the molecular events that lead to metastasis. We recently showed...
7.
Landreville S, Agapova O, Kneass Z, Salesse C, Harbour J
Pigment Cell Melanoma Res
. 2011 May;
24(3):430-7.
PMID: 21575142
Metastasis of tumor cells to distant organs is the leading cause of death in melanoma. Yet, the mechanisms of metastasis remain poorly understood. One key question is whether all cells...
8.
Agapova O, Person E, Harbour J
Clin Exp Metastasis
. 2010 Feb;
27(2):91-6.
PMID: 20127274
The inhibitor of DNA binding 2 (Id2) basic helix-loop-helix protein interacts genetically and physically with the pocket proteins (Rb, p107 and p130) and has been implicated as an oncogene. In...
9.
Landreville S, Agapova O, Harbour J
Future Oncol
. 2008 Oct;
4(5):629-36.
PMID: 18922120
Uveal melanoma is the most common primary cancer of the eye, and often results not only in vision loss, but also in metastatic death in up to half of patients....
10.
Kompass K, Agapova O, Li W, Kaufman P, Rasmussen C, Hernandez M
BMC Neurosci
. 2008 Sep;
9:93.
PMID: 18822132
Background: The nonhuman primate model of glaucomatous optic neuropathy most faithfully reproduces the human disease. We used high-density oligonucleotide arrays to investigate whole genome transcriptional changes occurring at the optic...