Ole William Petersen
Overview
Explore the profile of Ole William Petersen including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
1024
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Recent Articles
1.
Kohler K, Kim J, Villadsen R, Ronnov-Jessen L, Petersen O
Breast Cancer Res
. 2024 Dec;
26(1):183.
PMID: 39695857
Background: Basal-like breast cancer originates in luminal progenitors, frequently with an altered PI3K pathway, and focally in close association with genetically altered myoepithelial cells at the site of tumor initiation....
2.
Bagger M, Sjolund J, Kim J, Kohler K, Villadsen R, Jafari A, et al.
Breast Cancer Res
. 2024 Jan;
26(1):11.
PMID: 38229104
Background: Human breast cancer most frequently originates within a well-defined anatomical structure referred to as the terminal duct lobular unit (TDLU). This structure is endowed with its very own lobular...
3.
Kohler K, Goldhammer N, Demharter S, Pfisterer U, Khodosevich K, Ronnov-Jessen L, et al.
NPJ Breast Cancer
. 2022 Jul;
8(1):81.
PMID: 35821504
Normal breast luminal epithelial progenitors have been implicated as cell of origin in basal-like breast cancer, but their anatomical localization remains understudied. Here, we combine collection under the microscope of...
4.
Goldhammer N, Kim J, Villadsen R, Ronnov-Jessen L, Petersen O
Commun Biol
. 2022 Mar;
5(1):219.
PMID: 35273332
The myoepithelial (MEP) lineage of human breast comprises bipotent and multipotent progenitors in ducts and terminal duct lobular units (TDLUs). We here assess whether this heterogeneity impacts on oncogenic PIK3CA...
5.
Ronnov-Jessen L, Kim J, Goldhammer N, Klitgaard M, Smicius M, Bechmann M, et al.
Sci Rep
. 2021 Aug;
11(1):17232.
PMID: 34446796
Full term pregnancy at an early age is the only factor known to consistently protect against breast cancer. Because hormone receptor positive progenitors in the human breast relay endocrine signaling,...
6.
Morsing M, Kim J, Villadsen R, Goldhammer N, Jafari A, Kassem M, et al.
Breast Cancer Res
. 2020 Sep;
22(1):102.
PMID: 32993755
Background: Breast cancer arises within specific regions in the human breast referred to as the terminal duct lobular units (TDLUs). These are relatively dynamic structures characterized by sex hormone driven...
7.
Goldhammer N, Kim J, Timmermans-Wielenga V, Petersen O
Breast Cancer Res
. 2019 Dec;
21(1):141.
PMID: 31829259
Organoid cultures are increasingly used to model human cancers experimentally with a view to tailoring personalized medicine and predicting drug responses. Breast cancer is no exception, but in particular, primary...
8.
Bagger S, Hopkinson B, Pandey D, Bak M, Brydholm A, Villadsen R, et al.
Mol Cancer
. 2018 Dec;
17(1):171.
PMID: 30526604
Tumorigenesis is increasingly considered to rely on subclones of cells poised to undergo an epithelial to mesenchymal transition (EMT) program. We and others have provided evidence, however, that the tumorigenesis...
9.
Eichenlaub T, Villadsen R, Freitas F, Andrejeva D, Aldana B, Nguyen H, et al.
Curr Biol
. 2018 Oct;
28(20):3220-3228.e6.
PMID: 30293715
Cancers develop in a complex mutational landscape. Genetic models of tumor formation have been used to explore how combinations of mutations cooperate to promote tumor formation in vivo. Here, we...
10.
Fridriksdottir A, Villadsen R, Morsing M, Klitgaard M, Kim J, Petersen O, et al.
Proc Natl Acad Sci U S A
. 2017 Nov;
114(47):E10102-E10111.
PMID: 29109259
The human breast parenchyma consists of collecting ducts and terminal duct lobular units (TDLUs). The TDLU is the site of origin of most breast cancers. The reason for such focal...