Agla J Fridriksdottir
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Explore the profile of Agla J Fridriksdottir including associated specialties, affiliations and a list of published articles.
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10
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448
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Recent Articles
1.
Isberg O, Kim J, Fridriksdottir A, Morsing M, Timmermans-Wielenga V, Ronnov-Jessen L, et al.
Sci Rep
. 2020 Mar;
10(1):4788.
PMID: 32161318
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
2.
Isberg O, Kim J, Fridriksdottir A, Morsing M, Timmermans-Wielenga V, Ronnov-Jessen L, et al.
Sci Rep
. 2019 Oct;
9(1):14843.
PMID: 31619692
Human breast cancer is believed to arise in luminal progenitors within the normal breast. A subset of these are double positive (DP) for basal and luminal keratins and localizes to...
3.
Fridriksdottir A, Villadsen R, Morsing M, Klitgaard M, Kim J, Petersen O, et al.
Proc Natl Acad Sci U S A
. 2017 Nov;
114(47):E10102-E10111.
PMID: 29109259
The human breast parenchyma consists of collecting ducts and terminal duct lobular units (TDLUs). The TDLU is the site of origin of most breast cancers. The reason for such focal...
4.
Sorensen K, Meldgaard T, Melchjorsen C, Fridriksdottir A, Pedersen H, Petersen O, et al.
BMC Cancer
. 2017 Jan;
17(1):19.
PMID: 28056857
Background: One of the hallmarks of cancer is an altered energy metabolism, and here, mitochondria play a central role. Previous studies have indicated that some mitochondrial ribosomal proteins change their...
5.
Fridriksdottir A, Kim J, Villadsen R, Klitgaard M, Hopkinson B, Petersen O, et al.
Nat Commun
. 2015 Nov;
6:8786.
PMID: 26564780
Investigating the susceptibility of oestrogen receptor-positive (ER(pos)) normal human breast epithelial cells (HBECs) for clinical purposes or basic research awaits a proficient cell-based assay. Here we set out to identify...
6.
Larsen S, Meldgaard T, Fridriksdottir A, Lykkemark S, Poulsen P, Overgaard L, et al.
Immunol Res
. 2015 May;
62(3):263-72.
PMID: 25963139
Breast cancer tumors are composed of heterogeneous cell populations. These populations display a high variance in morphology, growth and metastatic propensity. They respond differently to therapeutic interventions, and some may...
7.
Garbe J, Pepin F, Pelissier F, Sputova K, Fridriksdottir A, Guo D, et al.
Cancer Res
. 2012 May;
72(14):3687-701.
PMID: 22552289
Women older than 50 years account for 75% of new breast cancer diagnoses, and the majority of these tumors are of a luminal subtype. Although age-associated changes, including endocrine profiles...
8.
Kim J, Villadsen R, Sorlie T, Fogh L, Gronlund S, Fridriksdottir A, et al.
Proc Natl Acad Sci U S A
. 2012 Mar;
109(16):6124-9.
PMID: 22454501
The majority of human breast cancers exhibit luminal epithelial differentiation. However, most aggressive behavior, including invasion and purported cancer stem cell activity, are considered characteristics of basal-like cells. We asked...
9.
de Neergaard M, Kim J, Villadsen R, Fridriksdottir A, Rank F, Timmermans-Wielenga V, et al.
Am J Pathol
. 2010 Feb;
176(3):1229-40.
PMID: 20133812
Tumor cells can activate stroma, yet the implication of this activation in terms of reciprocal induction of gene expression in tumor cells is poorly understood. Epithelial Stromal Interaction 1 (EPSTI1)...
10.
Villadsen R, Fridriksdottir A, Ronnov-Jessen L, Gudjonsson T, Rank F, LaBarge M, et al.
J Cell Biol
. 2007 Apr;
177(1):87-101.
PMID: 17420292
Cellular pathways that contribute to adult human mammary gland architecture and lineages have not been previously described. In this study, we identify a candidate stem cell niche in ducts and...