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Ok Hee Chai

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Articles 69
Citations 603
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Recent Articles
1.
Yu Z, Fan Y, Nguyen T, Piao C, Lee B, Lee S, et al.
Acta Biochim Biophys Sin (Shanghai) . 2024 Dec; PMID: 39719880
( . ) has long been a part of the human diet and medicine. Although . has been reported to have immunomodulatory, anti-inflammatory, anti-diabetic and antibacterial activities, its specific effect...
2.
Jin H, Meng R, Li C, Kim S, Chai O, Lee Y, et al.
Cancer Gene Ther . 2024 Sep; 31(11):1669-1687. PMID: 39251779
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide, with more than 800,000 deaths each year, and its 5-year survival rate is less than 12%. The role...
3.
Jin J, Nguyen T, Jiang Y, Yu Z, Song C, Lee S, et al.
Biomed Pharmacother . 2024 Apr; 174:116596. PMID: 38631146
Particulate matter (PM) significantly contributes to the global health crisis of respiratory diseases. It is known to induce and exacerbate conditions such as asthma and respiratory infections. Long exposure to...
4.
Yu Z, Fan Y, Nguyen T, Piao C, Lee B, Lee S, et al.
Immun Inflamm Dis . 2024 Mar; 12(3):e1215. PMID: 38488697
Background: Allergic rhinitis (AR) is the most prevalent form of atopic disease. Undaria pinnatifida has potent antioxidative, antidiabetic, and anti-inflammatory properties. Aims: We investigated the immunomodulatory effect of Undaria pinnatifida...
5.
Jin J, Fan Y, Nguyen T, Yu Z, Song C, Lee S, et al.
Foods . 2024 Feb; 13(4). PMID: 38397588
has traditionally been used as an herbal medicine due to its characteristics that protect against inflammation, hypertension, and mutagenesis. However, the effect of (CSE) on allergic rhinitis (AR) and its...
6.
Jiang Y, Nguyen T, Jin J, Yu Z, Song C, Chai O
Free Radic Biol Med . 2023 Dec; 212:207-219. PMID: 38147892
Asthma is a chronic obstructive airway condition and one of the most common non-communicable illnesses worldwide. Tectorigenin (Tec) is an isoflavonoid found in plants that possesses significant antioxidative and anti-inflammatory...
7.
Wu Y, Li C, Meng R, Jin H, Chai O, Kim S
Toxicol Appl Pharmacol . 2023 Dec; 482:116786. PMID: 38086440
Histone deacetylase (HDAC) inhibitors diminish carcinogenesis, metastasis, and cancer cell proliferation by inducing death in cancer cells. Tissue regeneration and organ development are highly dependent on the Hippo signaling pathway....
8.
Meng R, Li C, Hu D, Kwon S, Jin H, Chai O, et al.
Korean J Physiol Pharmacol . 2023 Aug; 27(5):493-511. PMID: 37641811
Hippo/YAP signaling hinders cancer progression. Inactivation of this pathway contributes to the development of esophageal cancer by activation of Akt. However, the possible interaction between Akt and Hippo/YAP pathways in...
9.
Jin J, Fan Y, Nguyen T, Yu Z, Song C, Lee S, et al.
Int J Mol Sci . 2023 Aug; 24(15). PMID: 37569890
(Asian knotweed) is a medicinal herb traditionally used to treat inflammation, among other conditions. However, the effects of root extract (FJE) on airway inflammation associated with combined allergic rhinitis and...
10.
Piaoa C, Zou S, Bui T, Song C, Chai O
Heliyon . 2023 Jul; 9(6):e17319. PMID: 37484363
Context: Saikosaponin D (SSD) is a commonly prescribed agent against inflammatory diseases in Asian countries. However, the anti-allergic inflammatory effect of SSD in allergic rhinitis (AR) model is not well...