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O N Ozes

Explore the profile of O N Ozes including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 1106
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Recent Articles
1.
Gorgisen G, Gulacar I, Ozes O
Cell Mol Biol (Noisy-le-grand) . 2017 Feb; 63(1):1-5. PMID: 28234626
Insulin Receptor Substrate (IRS) proteins are the main cytoplasmic adaptor molecules involved in transducing extracellular signals from receptors to downstream proteins. This protein family have pivotal roles on maintenance, distribution...
2.
Ozes A, Miller D, Ozes O, Fang F, Liu Y, Matei D, et al.
Oncogene . 2016 Apr; 35(41):5350-5361. PMID: 27041570
The transcription factor nuclear factor kappa B (NF-κB) and the long non-coding RNA (lncRNA) HOTAIR (HOX transcript antisense RNA) have diverse functional roles in cancer. In this study, we show...
3.
Gorgisen G, Balci M, Celik F, Gokkaya M, Ozdem S, Ozel D, et al.
Cell Mol Biol (Noisy-le-grand) . 2016 Mar; 62(2):25-30. PMID: 26950447
Insulin regulates the glucose homeostasis by inducing tyrosine phosphorylation of insulin receptor substrate (IRS) proteins. IRS1 is the best studied member of this family and insulin-induced Tyrosine phosphorylation of (YXXM)...
4.
Akca H, Ozes O
Scand J Clin Lab Invest . 2004 Jan; 63(7-8):505-12. PMID: 14743960
The tumor suppressor protein p53 is the most frequently mutated gene in human cancers. Since its discovery, p53 has evolved from a potential oncogene to the principal tumor suppressor in...
5.
Keser I, Kayisli O, Yesilipek A, Ozes O, Luleci G
Hemoglobin . 2002 Jan; 25(4):369-73. PMID: 11791869
A novel beta-thalassemia mutation, not previously reported in the literature, was identified by direct DNA sequencing of the beta-globin gene. Hematological investigation of a 26-year-old woman due to her increased...
6.
Ozes O, Akca H, Mayo L, Gustin J, Maehama T, Dixon J, et al.
Proc Natl Acad Sci U S A . 2001 Apr; 98(8):4640-5. PMID: 11287630
Tyrosine phosphorylation of insulin receptor substrate-1 (IRS-1) by the insulin receptor permits this docking protein to interact with signaling proteins that promote insulin action. Serine phosphorylation uncouples IRS-1 from the...
7.
Guo D, Wu L, DUNBAR J, Ozes O, Mayo L, Kessler K, et al.
J Biol Chem . 2001 Feb; 275(15):11216-21. PMID: 10753929
Vascular endothelial cell growth factor (VEGF) binds to and promotes the activation of one of its receptors, KDR. Once activated, KDR induces the tyrosine phosphorylation of cytoplasmic signaling proteins that...
8.
Lawless V, Zhang S, Ozes O, BRUNS H, Oldham I, Hoey T, et al.
J Immunol . 2000 Dec; 165(12):6803-8. PMID: 11120802
Stat4 is activated in response to IL-12. Most functions of IL-12, including the induction of IFN-gamma, are compromised in the absence of Stat4. Since the precise role of Stat4 in...
9.
Wu L, Mayo L, DUNBAR J, Kessler K, Ozes O, Warren R, et al.
J Biol Chem . 2000 Feb; 275(9):6059-62. PMID: 10692392
A protein that binds the intracellular domain of KDR (KDR-IC), a receptor for vascular endothelial cell growth factor (VEGF), was identified by two-hybrid screening. Two-hybrid mapping showed that the VEGF...
10.
Ozes O, Mayo L, Gustin J, Pfeffer S, Pfeffer L, Donner D
Nature . 1999 Sep; 401(6748):82-5. PMID: 10485710
Activation of the nuclear transcription factor NF-kappaB by inflammatory cytokines requires the successive action of NF-kappaB-inducing kinase (NIK) and an IKB-kinase (IKK) complex composed of IKKalpha and IKKbeta. Here we...