O Cuvillier
Overview
Explore the profile of O Cuvillier including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
1500
Followers
0
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Recent Articles
1.
Cherifi C, Latourte A, Vettorazzi S, Tuckermann J, Provot S, Ea H, et al.
Osteoarthritis Cartilage
. 2021 Jun;
29(9):1335-1345.
PMID: 34144150
Objective: Cartilage loss observed in osteoarthritis (OA) is prevented when osteoclasts in the subchondral bone are inhibited in mice. Here, we investigated the role of the osteoclast secretome and of...
2.
Lunardi P, Brizuela Madrid L, Beauval J, Roumiguie M, Soulie M, Cuvillier O, et al.
Prog Urol
. 2016 Aug;
26(8):484.
PMID: 27521734
No abstract available.
3.
Bouquerel P, Gstalder C, Muller D, Laurent J, Brizuela L, Sabbadini R, et al.
Oncogenesis
. 2016 Mar;
5:e209.
PMID: 26974204
The sphingosine kinase-1/sphingosine 1-phosphate (SphK1/S1P) signaling pathway has been reported to modulate the expression of the canonical transcription factor hypoxia-inducible HIF-1α in multiple cell lineages. HIF-2α is also frequently overexpressed...
4.
Lunardi P, Beauval J, Roumiguie M, Soulie M, Cuvillier O, Malavaud B
Prog Urol
. 2016 Feb;
26(3):159-67.
PMID: 26896427
Purpose: Tumor hypoxia and its biological consequence lead to microenvironment adaptation of tumor initiation, promotion and progression. The aim of the study was to observe the influence of hypoxia on...
5.
Bonhoure E, Lauret A, Barnes D, Martin C, Malavaud B, Kohama T, et al.
Leukemia
. 2008 Apr;
22(5):971-9.
PMID: 18401414
We examined the involvement of sphingosine kinase-1 (SphK1), which governs the ceramide/sphingosine-1-phosphate balance, in susceptibility to imatinib of either sensitive or resistant chronic myeloid leukemia cells. Imatinib-sensitive LAMA84-s displayed marked...
6.
Guillermet-Guibert J, Saint-Laurent N, Davenne L, Rochaix P, Cuvillier O, Culler M, et al.
Cell Death Differ
. 2006 Apr;
14(2):197-208.
PMID: 16645635
Somatostatin is a multifunctional hormone that modulates cell proliferation, differentiation and apoptosis. Mechanisms for somatostatin-induced apoptosis are at present mostly unsolved. Therefore, we investigated whether somatostatin receptor subtype 2 (sst2)...
7.
Bonhoure E, Pchejetski D, Aouali N, Morjani H, Levade T, Kohama T, et al.
Leukemia
. 2005 Nov;
20(1):95-102.
PMID: 16281067
We examined the involvement of sphingosine kinase-1, a critical regulator of the sphingolipid balance, in susceptibility to antineoplastic agents of either sensitive or multidrug-resistant acute myeloid leukemia cells. Contrary to...
8.
Levade T, Auge N, Veldman R, Cuvillier O, Negre-Salvayre A, Salvayre R
Circ Res
. 2001 Nov;
89(11):957-68.
PMID: 11717151
Sphingolipids have emerged as a new class of lipid mediators. In response to various extracellular stimuli, sphingolipid turnover can be stimulated in vascular cells and cardiac myocytes. Subsequent generation of...
9.
Cuvillier O, Levade T
Blood
. 2001 Oct;
98(9):2828-36.
PMID: 11675357
Sphingosine 1-phosphate (S-1P) has been implicated as a second messenger preventing apoptosis by counteracting activation of executioner caspases. Here it is reported that S-1P prevents apoptosis and executioner caspase-3 activation...
10.
Segui B, Cuvillier O, Adam-Klages S, Garcia V, Malagarie-Cazenave S, Leveque S, et al.
J Clin Invest
. 2001 Jul;
108(1):143-51.
PMID: 11435466
TNF-alpha is a pleiotropic cytokine activating several signaling pathways initiated at distinct intracellular domains of the TNF receptors. Although the C-terminal region is believed to be responsible for apoptosis induction,...