Nurulhuda Mustafa
Overview
Explore the profile of Nurulhuda Mustafa including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
220
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Recent Articles
1.
Indran I, Paranthaman P, Gupta N, Mustafa N
Med Teach
. 2023 Dec;
46(8):1021-1026.
PMID: 38146711
Background: Crafting quality assessment questions in medical education is a crucial yet time-consuming, expertise-driven undertaking that calls for innovative solutions. Large language models (LLMs), such as ChatGPT (Chat Generative Pre-Trained...
2.
Mustafa N, Azaman M, Ng G, Chng W
Biomolecules
. 2022 Sep;
12(9).
PMID: 36139103
CD38 was first discovered as a T-cell antigen and has since been found ubiquitously expressed in various hematopoietic cells, including plasma cells, NK cells, B cells, and granulocytes. More importantly,...
3.
Ramalingam A, Mustafa N, Chng W, Medimagh M, Sambandam S, Issaoui N
Biomolecules
. 2022 Aug;
12(8).
PMID: 36008987
Piperidine pharmacophore-containing compounds have demonstrated therapeutic efficacy against a range of diseases and are now being investigated in cancer. A series of 3-chloro-3-methyl-2,6-diarylpiperidin-4-ones, compounds (-) were designed and synthesized for...
4.
Mustafa N, Sook Ling L, Abdul Razak S
F1000Res
. 2022 May;
10:1274.
PMID: 35528953
: Customer churn is a term that refers to the rate at which customers leave the business. Churn could be due to various factors, including switching to a competitor, cancelling...
5.
De Mel S, Mustafa N, Selvarajan V, Azaman M, Jaynes P, Venguidessane S, et al.
PLoS One
. 2022 Jan;
17(1):e0261469.
PMID: 35077445
B-cell receptor (BCR) signalling is critical for the survival of B-cell lymphomas and is a therapeutic target of drugs such as Ibrutinib. However, the role of T-cell receptor (TCR) signalling...
6.
Mustafa N, Nee A, Chooi J, Toh S, Chung T, Selvarajan V, et al.
J Immunother Cancer
. 2021 Jul;
9(7).
PMID: 34215687
Background: The potential therapeutic efficacy of daratumumab in natural killer T-cell lymphoma (NKTL) was highlighted when its off-label usage produced sustained remission in a patient with highly refractory disease. This...
7.
Soumyanarayanan U, Ramanujulu P, Mustafa N, Haider S, Nee A, Tong J, et al.
Eur J Med Chem
. 2019 Oct;
184:111755.
PMID: 31627059
Herein, we report the discovery of a dual histone deacetylase inhibitor displaying a unique HDAC3/6 selectivity profile. An initial strategy to merge two epigenetic pharmacophores resulted in the discovery of...
8.
Li B, Yan J, Phyu T, Fan S, Chung T, Mustafa N, et al.
Blood
. 2019 Aug;
134(23):2046-2058.
PMID: 31434700
Oncogenic EZH2 is overexpressed and extensively involved in the pathophysiology of different cancers including extranodal natural killer/T-cell lymphoma (NKTL). However, the mechanisms regarding EZH2 upregulation is poorly understood, and it...
9.
Chu-Farseeva Y, Mustafa N, Poulsen A, Tan E, Yen J, Chng W, et al.
Eur J Med Chem
. 2018 Sep;
158:593-619.
PMID: 30243158
Specifically blocking more than one oncogenic pathway simultaneously in a cancer cell with a combination of different drugs is the mainstay of the majority of cancer treatments. Being able to...
10.
Shanmugam M, Ahn K, Lee J, Kannaiyan R, Mustafa N, Manu K, et al.
Front Pharmacol
. 2018 May;
9:365.
PMID: 29773987
Several lines of evidence have demonstrated that deregulated activation of NF-κB plays a pivotal role in the initiation and progression of a variety of cancers including multiple myeloma (MM). Therefore,...