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Nuno Rocha

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Articles 43
Citations 1336
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Recent Articles
11.
Laria A, Messineo S, Arcidiacono B, Varano M, Chiefari E, Semple R, et al.
Proteomics . 2018 Feb; 18(7):e1700260. PMID: 29466620
In the obese state, as adipose tissue expands, adipocytes become hypoxic and dysfunctional, leading to changes in the pattern of adipocyte-secreted proteins. To better understand the role of hypoxia in...
12.
Lattari E, Rosa Filho B, Junior S, Murillo-Rodriguez E, Rocha N, Machado S, et al.
J Strength Cond Res . 2018 Jan; 34(1):89-96. PMID: 29329154
Lattari, E, Rosa Filho, BJ, Fonseca Junior, SJ, Murillo-Rodriguez, E, Rocha, N, Machado, S, and Maranhão Neto, GA. Effects on volume load and ratings of perceived exertion in individuals' advanced...
13.
Monteiro B, Monteiro S, Candida M, Adler N, Paes F, Rocha N, et al.
Clin Pract Epidemiol Ment Health . 2018 Jan; 13:213-219. PMID: 29299044
The Brain-Derived Neurotrofic Factor (BDNF) is one of the most important neurotrophins in the brain and it is suggested influences the activity of the serotonergic, noradrenergic and dopaminergic pathways. In...
14.
Rocha N, Payne F, Huang-Doran I, Sleigh A, Fawcett K, Adams C, et al.
Sci Rep . 2017 Dec; 7(1):17593. PMID: 29242557
Common genetic variants at the ARL15 locus are associated with plasma adiponectin, insulin and HDL cholesterol concentrations, obesity, and coronary atherosclerosis. The ARL15 gene encodes a small GTP-binding protein whose...
15.
Machado S, Filho A, Wilbert M, Barbieri G, Almeida V, Gurgel A, et al.
Clin Pract Epidemiol Ment Health . 2017 Dec; 13:181-184. PMID: 29238394
Introduction: Mental health decline is one of the main responsible factors for augments in health care costs, and diagnosis of Alzheimer's disease (AD). Some studies stated physical exercise is useful...
16.
Legey S, Aquino F, Lamego M, Paes F, Nardi A, Neto G, et al.
Clin Pract Epidemiol Ment Health . 2017 Oct; 13:82-91. PMID: 29081825
Background: Physical activity level (PAL) is known to play an important role in reducing risk factors associated with sedentarism, in addition to improving the mental health and health-related quality of...
17.
Chen J, Goh K, Rocha N, Groeneveld M, Minic M, Barrett T, et al.
Dis Model Mech . 2017 Oct; 10(12):1411-1420. PMID: 28982679
Adipose tissue is the primary tissue affected in most single gene forms of severe insulin resistance, and growing evidence has implicated it as a site at which many risk alleles...
18.
Machado S, Sancassiani F, Paes F, Rocha N, Murillo-Rodriguez E, Nardi A
Int Rev Psychiatry . 2017 Sep; 29(5):436-444. PMID: 28893114
The association between panic disorder (PD) and cardiovascular diseases (CVD) has been extensively studied in recent years and, although some studies have shown anxiety disorders co-existing or increasing the risk...
19.
Leiter S, Parker V, Welters A, Knox R, Rocha N, Clark G, et al.
Eur J Endocrinol . 2017 Jun; 177(2):175-186. PMID: 28566443
Objective: Genetic activation of the insulin signal-transducing kinase causes syndromic hypoketotic hypoglycaemia without elevated insulin. Mosaic activating mutations in class 1A phospatidylinositol-3-kinase (PI3K), upstream from AKT2 in insulin signalling, are...
20.
Minic M, Rocha N, Harris J, Groeneveld M, Leiter S, Wareham N, et al.
J Clin Endocrinol Metab . 2017 May; 102(8):2914-2921. PMID: 28541532
Context: The activating p.Glu17Lys mutation in AKT2, a kinase mediating many of insulin's metabolic actions, causes hypoinsulinemic hypoglycemia and left-sided hemihypertrophy. The wider metabolic profile and longer-term natural history of...