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Nordin D Zandhuis

Explore the profile of Nordin D Zandhuis including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Verkerk T, de Waard A, Koomen S, Sanders J, Jorritsma T, Pappot A, et al.
Eur J Immunol . 2024 Dec; 55(2):e202451129. PMID: 39655358
The development of an effective antitumor response relies on the synergistic actions of various immune cells that recognize tumor cells via distinct receptors. Tumors, however, often manipulate receptor-ligand interactions to...
2.
Zandhuis N, Guislain A, Popalzij A, Engels S, Popovic B, Turner M, et al.
Eur J Immunol . 2024 Jul; 54(10):e2451018. PMID: 38980256
CD8 T cells kill target cells by releasing cytotoxic molecules and proinflammatory cytokines, such as TNF and IFN-γ. The magnitude and duration of cytokine production are defined by posttranscriptional regulation,...
3.
Foskolou I, Cunha P, Sanchez-Lopez E, Minogue E, Nicolet B, Guislain A, et al.
Cell Rep . 2023 Aug; 42(9):113013. PMID: 37632752
2-Hydroxyglutarate (2HG) is a byproduct of the tricarboxylic acid (TCA) cycle and is readily detected in the tissues of healthy individuals. 2HG is found in two enantiomeric forms: S-2HG and...
4.
Imianowski C, Whiteside S, Lozano T, Evans A, Benson J, Courreges C, et al.
J Exp Med . 2022 Sep; 219(12). PMID: 36178457
Natural killer (NK) cells are critical to immune surveillance against infections and cancer. Their role in immune surveillance requires that NK cells are present within tissues in a quiescent state....
5.
Zandhuis N, Nicolet B, Wolkers M
Front Immunol . 2021 Dec; 12:717324. PMID: 34867946
B cells and T cells are key players in the defence against infections and malignancies. To exert their function, B cells and T cells differentiate into effector and memory cells....
6.
Nicolet B, Zandhuis N, Lattanzio V, Wolkers M
Immunol Rev . 2021 Sep; 304(1):10-29. PMID: 34486113
T cell homeostasis, T cell differentiation, and T cell effector function rely on the constant fine-tuning of gene expression. To alter the T cell state, substantial remodeling of the proteome...