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Nolan R Filipenko

Explore the profile of Nolan R Filipenko including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 265
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Recent Articles
1.
Troussard A, McDonald P, Wederell E, Mawji N, Filipenko N, Gelmon K, et al.
Cancer Res . 2006 Jan; 66(1):393-403. PMID: 16397254
The emerging paradigm of "oncogene addiction" has been called an Achilles' heel of cancer that can be exploited therapeutically. Here, we show that integrin-linked kinase (ILK), which is either activated...
2.
Filipenko N, Attwell S, Roskelley C, Dedhar S
Oncogene . 2005 May; 24(38):5837-49. PMID: 15897874
Cell spreading and migration are regulated in a Rho family GTPase-dependent manner by growth factors and integrin-mediated cell-extracellular matrix (ECM) interactions. The molecular mechanisms involved in the ECM- and growth...
3.
Filipenko N, Macleod T, Yoon C, Waisman D
J Biol Chem . 2003 Dec; 279(10):8723-31. PMID: 14672933
Annexin A2 (ANXA2) is a Ca(2+)-binding protein that is up-regulated in virally transformed cell lines and in human tumors. Here, we show that ANXA2 binds directly to both ribonucleotide homopolymers...
4.
Caplan J, Filipenko N, Fitzpatrick S, Waisman D
J Biol Chem . 2003 Dec; 279(9):7740-50. PMID: 14668336
The annexin A2-S100A10 heterotetramer (AIIt) is a multifunctional Ca(2+)-dependent, phospholipid-binding, and F-actin-binding phosphoprotein composed of two annexin A2 subunits and two S100A10 subunits. It was reported previously that oxidative stress...
5.
Macleod T, Kwon M, Filipenko N, Waisman D
J Biol Chem . 2003 May; 278(28):25577-84. PMID: 12730231
Annexin A2 (p36) is a highly alpha-helical molecule that consists of two opposing sides, a convex side that contains the phospholipid-binding sites and a concave side, which faces the extracellular...
6.
Fogg D, Bridges D, Cheung K, Kassam G, Filipenko N, Choi K, et al.
Biochemistry . 2002 Apr; 41(15):4953-61. PMID: 11939791
The Ca(2+)-dependent phospholipid-binding protein annexin II heterotetramer (AIIt) is composed of two copies of annexin II and a p11 dimer. The interaction of the carboxyl-terminal lysine residues of the p11...
7.
Kang H, Filipenko N, Kassam G, Waisman D
Methods Mol Biol . 2002 Feb; 172:225-34. PMID: 11833350
No abstract available.
8.
Kwon M, Caplan J, Filipenko N, Choi K, Fitzpatrick S, Zhang L, et al.
J Biol Chem . 2002 Jan; 277(13):10903-11. PMID: 11781322
Annexin II heterotetramer (AIIt) is a Ca(2+)- and phospholipid-binding protein that consists of two copies of a p36 and p11 subunit. AIIt regulates the production and autoproteolysis of plasmin at...