Nolan McClain
Overview
Explore the profile of Nolan McClain including associated specialties, affiliations and a list of published articles.
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6
Citations
61
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Recent Articles
1.
Lawal O, Niihori M, James J, Hinkle A, Sano T, McClain N, et al.
Am J Respir Cell Mol Biol
. 2025 Mar;
PMID: 40085493
High Mobility Group Box 1 (HMGB1) is a nuclear protein released from damaged cells and implicated in the pathogenesis of Pulmonary Arterial Hypertension (PAH) through activation of pro-inflammatory and pro-survival...
2.
Niihori M, James J, Varghese M, McClain N, Lawal O, Philip R, et al.
J Exp Med
. 2024 Sep;
221(11).
PMID: 39320470
Impaired pulmonary angiogenesis plays a pivotal role in the progression of pulmonary arterial hypertension (PAH) and patient mortality, yet the molecular mechanisms driving this process remain enigmatic. Our study uncovered...
3.
James J, Dekan A, Niihori M, McClain N, Varghese M, Bharti D, et al.
Res Sq
. 2023 May;
PMID: 37205391
The role of the lung's microcirculation and capillary endothelial cells in normal physiology and the pathobiology of pulmonary diseases is unequivocally vital. The recent discovery of molecularly distinct aerocytes and...
4.
Zemskova M, McClain N, Niihori M, Varghese M, James J, Rafikov R, et al.
Hypertension
. 2020 Oct;
76(6):1787-1799.
PMID: 33012199
Damage-associated molecular patterns, such as HMGB1 (high mobility group box 1), play a well-recognized role in the development of pulmonary arterial hypertension (PAH), a progressive fatal disease of the pulmonary...
5.
Zemskova M, Kurdyukov S, James J, McClain N, Rafikov R, Rafikova O
PLoS One
. 2020 Apr;
15(4):e0231267.
PMID: 32271800
Women are known to be associated with a higher susceptibility to pulmonary arterial hypertension (PAH). In contrast, male PAH patients have a worse survival prognosis. In this study, we investigated...
6.
Rafikov R, James J, McClain N, Tofovic S, Rafikova O
Antioxidants (Basel)
. 2019 May;
8(5).
PMID: 31100969
Pulmonary arterial hypertension (PAH) is one of the diseases with a well-established gender dimorphism. The prevalence of PAH is increased in females with a ratio of 4:1, while poor survival...
7.
Rafikov R, McBride M, Zemskova M, Kurdyukov S, McClain N, Niihori M, et al.
Am J Physiol Lung Cell Mol Physiol
. 2019 Jan;
316(3):L428-L444.
PMID: 30604625
Pulmonary arterial hypertension (PAH) is a lethal disease characterized by progressive pulmonary vascular remodeling. The receptor for advanced glycation end products (RAGE) plays an important role in PAH by promoting...