Noel G Morgan
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Explore the profile of Noel G Morgan including associated specialties, affiliations and a list of published articles.
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Articles
117
Citations
3081
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Recent Articles
1.
Akhbari P, Perez-Hernandez J, Russell M, Dhayal S, Leslie K, Hunter S, et al.
Diabetes
. 2025 Mar;
PMID: 40063529
HLA class I (HLA-I) molecules present intracellular antigenic peptides to CD8+ T lymphocytes during immune surveillance. In donors with type 1 diabetes, hyperexpression of HLA-I occurs in islets with residual...
2.
Verschueren van Rees N, Ashwin P, McMullan C, Krogvold L, Dahl-Jorgensen K, Morgan N, et al.
Diabetologia
. 2025 Feb;
PMID: 40011232
Aims/hypothesis: The organisation and cellular architecture of islets of Langerhans are critical to the physiological regulation of hormone secretion but it is debated whether human islets adhere to the characteristic...
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4.
Leslie K, Lekka C, Richardson S, Russell M, Morgan N
Diabetes
. 2024 Jun;
73(9):1473-1485.
PMID: 38869827
Article Highlights:
5.
MacCalman A, De Franco E, Franklin A, Flaxman C, Richardson S, Murrall K, et al.
BMC Genomics
. 2024 Jun;
25(1):553.
PMID: 38831310
Development of the human pancreas requires the precise temporal control of gene expression via epigenetic mechanisms and the binding of key transcription factors. We quantified genome-wide patterns of DNA methylation...
6.
Ellis M, Lekka C, Holden K, Tulmin H, Seedat F, OBrien D, et al.
Acta Neuropathol
. 2024 May;
147(1):87.
PMID: 38761203
Antibodies are essential research tools whose performance directly impacts research conclusions and reproducibility. Owing to its central role in Alzheimer's disease and other dementias, hundreds of distinct antibody clones have...
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Coomans de Brachene A, Alvelos M, Szymczak F, Zimath P, Castela A, Marmontel de Souza B, et al.
Diabetologia
. 2024 Feb;
67(5):908-927.
PMID: 38409439
Aims/hypothesis: The proinflammatory cytokines IFN-α, IFN-γ, IL-1β and TNF-α may contribute to innate and adaptive immune responses during insulitis in type 1 diabetes and therefore represent attractive therapeutic targets to...
9.
Morgan N
Eur J Endocrinol
. 2024 Jan;
PMID: 38231086
Type 1 diabetes is caused by a deficiency of insulin secretion which has been considered traditionally as the outcome of a precipitous decline in the viability of β-cells in the...
10.
Russell M, Richardson S, Morgan N
Front Endocrinol (Lausanne)
. 2023 Oct;
14:1270325.
PMID: 37867531
The hyperexpression of human leukocyte antigen class I (HLA-I) molecules on pancreatic beta-cells is widely accepted as a hallmark feature of type 1 diabetes pathogenesis. This response is important clinically...