Nikhil P Krishnan
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Explore the profile of Nikhil P Krishnan including associated specialties, affiliations and a list of published articles.
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5
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82
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Recent Articles
1.
Gopalakrishnan V, Crozier D, Card K, Chick L, Krishnan N, McClure E, et al.
Elife
. 2022 Nov;
11.
PMID: 36317871
A morbidostat is a bioreactor that uses antibiotics to control the growth of bacteria, making it well-suited for studying the evolution of antibiotic resistance. However, morbidostats are often too expensive...
2.
Rojas L, Yasmin M, Benjamino J, Marshall S, DeRonde K, Krishnan N, et al.
PLoS One
. 2022 Mar;
17(3):e0265129.
PMID: 35358221
Background: Pseudomonas aeruginosa is a persistent and difficult-to-treat pathogen in many patients, especially those with Cystic Fibrosis (CF). Herein, we describe a longitudinal analysis of a series of multidrug resistant...
3.
Vijayaraghavan J, Kumar V, Krishnan N, Kaufhold R, Zeng X, Lin J, et al.
PLoS One
. 2018 May;
13(5):e0197136.
PMID: 29758058
The bacterial soluble lytic transglycosylase (LT) breaks down the peptidoglycan (PG) layer during processes such as cell division. We present here crystal structures of the soluble LT Cj0843 from Campylobacter...
4.
Nguyen N, Krishnan N, Rojas L, Prati F, Caselli E, Romagnoli C, et al.
Antimicrob Agents Chemother
. 2016 Jan;
60(3):1760-6.
PMID: 26729491
Resistance to expanded-spectrum cephalosporins and carbapenems has rendered certain strains of Klebsiella pneumoniae the most problematic pathogens infecting patients in the hospital and community. This broad-spectrum resistance to β-lactamases emerges...
5.
Krishnan N, Nguyen N, Papp-Wallace K, Bonomo R, van den Akker F
PLoS One
. 2015 Sep;
10(9):e0136813.
PMID: 26340563
β-Lactamase inhibition is an important clinical strategy in overcoming β-lactamase-mediated resistance to β-lactam antibiotics in Gram negative bacteria. A new β-lactamase inhibitor, avibactam, is entering the clinical arena and promising...