Nigel Roome
Overview
Explore the profile of Nigel Roome including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
8
Citations
239
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Bartels T, Wase K, Heinrichs M, Stolte M, Roome N, Scherer P, et al.
Toxicol Pathol
. 2016 Sep;
44(7):931-46.
PMID: 27663844
The toxicological profile of insulins is exclusively due to exaggerated pharmacology resulting in hypoglycemic findings. Insulin analogues displaying modifications and aimed at improving pharmacokinetics do not induce different toxicity. The...
2.
Guan P, Olaharski A, Fielden M, Roome N, Dragan Y, Sina J
Expert Rev Clin Pharmacol
. 2014 Jan;
1(6):759-71.
PMID: 24410606
The screening of drug candidates to assess their carcinogenic potential has long been a challenge for drug development. While genotoxic compounds can be readily detected with a battery of standard...
3.
Lezmi S, Rokh N, Saint-Macary G, Pino M, Sallez V, Thevenard F, et al.
Toxicology
. 2013 Apr;
308:50-9.
PMID: 23567313
Retinal toxicity of chloroquine has been known for several years, but the mechanism(s) of toxicity remain controversial; some author support the idea that the binding of chloroquine to melanin pigments...
4.
Fielden M, Nie A, McMillian M, Elangbam C, Trela B, Yang Y, et al.
Toxicol Sci
. 2008 Feb;
103(1):28-34.
PMID: 18281259
The Critical Path Institute recently established the Predictive Safety Testing Consortium, a collaboration between several companies and the U.S. Food and Drug Administration, aimed at evaluating and qualifying biomarkers for...
5.
Society of Toxicologic Pathology position paper: organ weight recommendations for toxicology studies
Sellers R, Morton D, Michael B, Roome N, Johnson J, Yano B, et al.
Toxicol Pathol
. 2007 Sep;
35(5):751-5.
PMID: 17849358
The evaluation of organ weights in toxicology studies is an integral component in the assessment of pharmaceuticals, chemicals, and medical devices. The Society of Toxicologic Pathology (STP) has created recommendations...
6.
Michael B, Yano B, Sellers R, Perry R, Morton D, Roome N, et al.
Toxicol Pathol
. 2007 Sep;
35(5):742-50.
PMID: 17849357
The Society of Toxicologic Pathology convened a working group to evaluate current practices regarding organ weights in toxicology studies. A survey was distributed to pharmaceutical, veterinary, chemical, food/nutritional and consumer...
7.
Morton D, Kemp R, Francke-Carroll S, Jensen K, McCartney J, Monticello T, et al.
Toxicol Pathol
. 2006 Dec;
34(6):806-9.
PMID: 17162539
No abstract available.
8.
Lorrain J, Lechaire I, Gauffeny C, Masson R, Roome N, Herault J, et al.
J Pharmacol Exp Ther
. 2004 Jan;
309(1):235-40.
PMID: 14718579
SanOrg123781A is a synthetic hexadecasaccharide that displays antithrombin-dependent inhibition of factor Xa and thrombin and potent antithrombotic effects. The antithrombotic activity of SanOrg123781A has been studied in a new mouse...