Nigel M Williams
Overview
Explore the profile of Nigel M Williams including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
91
Citations
7913
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Tan M, Iwaki H, Bandres-Ciga S, Sosero Y, Shoai M, Brockmann K, et al.
medRxiv
. 2025 Feb;
PMID: 39974079
Polygenic risk scores (PRS) in Parkinson's disease (PD) are associated with disease risk. Recently, pathway-specific PRS have been created to take advantage of annotations inking variants to biological pathways or...
2.
Wu L, Real R, Martinez-Carrasco A, Chia R, Lawton M, Shoai M, et al.
Brain Commun
. 2024 Jul;
6(4):fcae190.
PMID: 38978726
Up to 80% of Parkinson's disease patients develop dementia, but time to dementia varies widely from motor symptom onset. Dementia with Lewy bodies presents with clinical features similar to Parkinson's...
3.
Tan M, Lawton M, Pollard M, Brown E, Real R, Carrasco A, et al.
NPJ Parkinsons Dis
. 2024 Jun;
10(1):113.
PMID: 38849413
There are 90 independent genome-wide significant genetic risk variants for Parkinson's disease (PD) but currently only five nominated loci for PD progression. The biology of PD progression is likely to...
4.
Martinez-Carrasco A, Real R, Lawton M, Iwaki H, Tan M, Wu L, et al.
NPJ Parkinsons Dis
. 2023 Aug;
9(1):128.
PMID: 37652906
The genetic basis of levodopa-induced-dyskinesia (LiD) is poorly understood, and there have been few well-powered genome-wide studies. We performed a genome-wide survival meta-analyses to study the effect of genetic variation...
5.
Martinez-Carrasco A, Real R, Lawton M, Iwaki H, Tan M, Wu L, et al.
medRxiv
. 2023 Jul;
PMID: 37425912
Importance: Forty percent of Parkinson's disease patients develop levodopa-induced-dyskinesia (LiD) within 4 years of starting levodopa. The genetic basis of LiD remains poorly understood, and there have been few well...
6.
Millrine D, Cardus Figueras A, Uceda Fernandez J, Andrews R, Szomolay B, Cossins B, et al.
J Immunol
. 2023 Jun;
211(2):274-286.
PMID: 37272871
Cytokines that signal via STAT1 and STAT3 transcription factors instruct decisions affecting tissue homeostasis, antimicrobial host defense, and inflammation-induced tissue injury. To understand the coordination of these activities, we applied...
7.
Lin J, Zhao Y, Jabalameli M, Nguyen N, Mitra J, Swillen A, et al.
Mol Psychiatry
. 2023 Mar;
28(5):2071-2080.
PMID: 36869225
22q11.2 deletion is one of the strongest known genetic risk factors for schizophrenia. Recent whole-genome sequencing of schizophrenia cases and controls with this deletion provided an unprecedented opportunity to identify...
8.
Lobanov S, McAllister B, McDade-Kumar M, Landwehrmeyer G, Orth M, Rosser A, et al.
NPJ Genom Med
. 2022 Sep;
7(1):53.
PMID: 36064847
Huntington's disease is caused by an expanded CAG tract in HTT. The length of the CAG tract accounts for over half the variance in age at onset of disease, and...
9.
Trubetskoy V, Pardinas A, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli T, et al.
Nature
. 2022 Apr;
604(7906):502-508.
PMID: 35396580
Schizophrenia has a heritability of 60-80%, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and...
10.
McAllister B, Donaldson J, Binda C, Powell S, Chughtai U, Edwards G, et al.
Nat Neurosci
. 2022 Apr;
25(4):446-457.
PMID: 35379994
The age at onset of motor symptoms in Huntington's disease (HD) is driven by HTT CAG repeat length but modified by other genes. In this study, we used exome sequencing...