Nicolien C de Clercq
Overview
Explore the profile of Nicolien C de Clercq including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
329
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Recent Articles
1.
Warmbrunn M, Bahrar H, de Clercq N, Koopen A, de Groot P, Rutten J, et al.
Nutrients
. 2024 Jun;
16(12).
PMID: 38931177
Context/objective: In order to better understand which metabolic differences are related to insulin resistance in metabolic syndrome (MetSyn), we used hyperinsulinemic-euglycemic (HE) clamps in individuals with MetSyn and related peripheral...
2.
Ende T, de Clercq N, Davids M, Goedegebuure R, Doeve B, Ebrahimi G, et al.
J Natl Cancer Inst
. 2024 Jun;
116(11):1834-1844.
PMID: 38924513
Background: The microbiome has been associated with chemotherapy and immune checkpoint inhibitor efficacy. How this pertains to resectable esophageal carcinoma is unknown. Our aim was to identify microbial signatures in...
3.
Warmbrunn M, Koopen A, de Clercq N, de Groot P, Kootte R, Bouter K, et al.
Metabolites
. 2021 Apr;
11(4).
PMID: 33924347
Metabolic syndrome (MetSyn) is an important risk factor for type 2 diabetes and cardiovascular diseases (CVD). This study aimed to find distinct plasma metabolite profiles between insulin-resistant and non-insulin resistant...
4.
de Clercq N, Ende T, Prodan A, Hemke R, Davids M, Pedersen H, et al.
Clin Cancer Res
. 2021 Apr;
27(13):3784-3792.
PMID: 33883174
Purpose: Cachexia is a multifactorial syndrome, associated with poor survival in patients with cancer, and is influenced by the gut microbiota. We investigated the effects of fecal microbiota transplantation (FMT)...
5.
Ende T, de Clercq N, van Berge Henegouwen M, Gisbertz S, Geijsen E, Verhoeven R, et al.
Clin Cancer Res
. 2021 Jan;
27(12):3351-3359.
PMID: 33504550
Purpose: The CROSS trial established neoadjuvant chemoradiotherapy (nCRT) for patients with resectable esophageal adenocarcinoma (rEAC). In the PERFECT trial, we investigated the feasibility and efficacy of nCRT combined with programmed-death...
6.
Koopen A, de Clercq N, Warmbrunn M, Herrema H, Davids M, de Groot P, et al.
Nutrients
. 2020 Aug;
12(8).
PMID: 32752028
Plasma metabolites affect a range of metabolic functions in humans, including insulin sensitivity (IS). A subset of these plasma metabolites is modified by the gut microbiota. To identify potential microbial-metabolite...
7.
Bakker G, Schnitzler J, Bekkering S, de Clercq N, Koopen A, Hartstra A, et al.
Physiol Rep
. 2019 Aug;
7(16):e14199.
PMID: 31423751
Intake of a high-fat meal induces a systemic inflammatory response in the postprandial which is augmented in obese subjects. However, the underlying mechanisms of this response have not been fully...
8.
de Clercq N, Frissen M, Davids M, Groen A, Nieuwdorp M
Psychother Psychosom
. 2019 Jan;
88(1):58-60.
PMID: 30625497
No abstract available.
9.
Fluitman K, de Clercq N, Keijser B, Visser M, Nieuwdorp M, IJzerman R
Expert Rev Endocrinol Metab
. 2018 Aug;
12(3):215-226.
PMID: 30063458
Malnutrition refers to both over- and undernutrition and results from a disruption in energy balance. It affects one in three people worldwide and is associated with increased morbidity and mortality....
10.
Emanuel A, de Clercq N, Koopen A, van Poelgeest E, Serlie M, van Raalte D, et al.
Diabetes Obes Metab
. 2018 Jun;
20(11):2523-2531.
PMID: 29885045
Aims: In type 2 diabetes impaired insulin-induced muscle perfusion is thought to contribute to reduced whole-body glucose uptake. In this study, we examined the effects of iloprost, a stable prostacyclin...