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Nicole Zoratto

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Articles 16
Citations 106
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Recent Articles
1.
Paoletti L, Ferrigno G, Zoratto N, Secci D, Di Meo C, Matricardi P
Gels . 2024 Dec; 10(12). PMID: 39727531
The need for new biomaterials to meet the needs of advanced healthcare therapies is constantly increasing. Polysaccharide-based matrices are considered extremely promising because of their biocompatibility and soft structure; however,...
2.
Wang J, Di Risola D, Mattioli R, Zoratto N, Mosca L, Di Meo C, et al.
Int J Pharm . 2024 Nov; 668:124978. PMID: 39571768
Topical application of the glucocorticoid betamethasone (BM) is a common treatment for inflammatory-related skin diseases, such as psoriasis. However, enhancing its bioavailability remains challenging due to poor skin permeability. Herein,...
3.
Geisshusler S, Nilsson F, Ziak N, Kotkowska Z, Paolucci M, Green Buzhor M, et al.
Eur J Pharm Biopharm . 2024 Mar; 198:114249. PMID: 38467334
In recent years, microneedles (MNs) have gained considerable interest in drug formulation due to their non-invasive and patient-friendly nature. Dissolving MNs have emerged as a promising approach to enhance drug...
4.
Zoratto N, Klein-Cerrejon D, Gao D, Inchiparambil T, Sachs D, Luo Z, et al.
Adv Sci (Weinh) . 2024 Mar; 11(18):e2308809. PMID: 38450888
Conventional venipuncture is invasive and challenging in low and middle-income countries. Conversely, point-of-care devices paired with fingersticks, although less invasive, suffer from high variability and low blood volume collection. Recently...
5.
Luo Z, Klein Cerrejon D, Romer S, Zoratto N, Leroux J
Sci Transl Med . 2023 Sep; 15(715):eabq1887. PMID: 37756378
Biopharmaceuticals, including proteins and peptides, have revolutionized the treatment of a wide range of diseases, from diabetes and cardiovascular disorders to virus infections and cancer. Despite their efficacy, most of...
6.
Krivitsky V, Krivitsky A, Mantella V, Ben-Yehuda Greenwald M, Sankar D, Betschmann J, et al.
Adv Mater . 2023 Jul; 35(44):e2212000. PMID: 37452635
Extracellular vesicles (EVs) are secreted by all living cells and are found in body fluids. They exert numerous physiological and pathological functions and serve as cargo shuttles. Due to their...
7.
Di Matteo S, Di Meo C, Carpino G, Zoratto N, Cardinale V, Nevi L, et al.
Drug Deliv Transl Res . 2022 Feb; 12(8):1959-1973. PMID: 35226290
A major function of the intrahepatic biliary epithelium is bicarbonate excretion in bile. Recent reports indicate that budesonide, a corticosteroid with high receptor affinity and hepatic first pass clearance, increases...
8.
Zoratto N, Forcina L, Matassa R, Mosca L, Familiari G, Musaro A, et al.
Pharmaceutics . 2021 Nov; 13(11). PMID: 34834195
The anatomy and physiology of the eye strongly limit the bioavailability of locally administered drugs. The entrapment of therapeutics into nanocarriers represents an effective strategy for the topical treatment of...
9.
Stagno V, Genova C, Zoratto N, Favero G, Capuani S
Molecules . 2021 Jul; 26(12). PMID: 34204336
In this work, we investigated the potential of PVA-borax hydrogel for cleaning limestones and the dependence of the cleaning on the porosity of the rock and on the action time...
10.
Zoratto N, Di Lisa D, de Rutte J, Sakib M, Silva A, Tamayol A, et al.
Bioeng Transl Med . 2020 Oct; 5(3):e10180. PMID: 33005742
Converting biopolymers to extracellular matrix (ECM)-mimetic hydrogel-based scaffolds has provided invaluable opportunities to design in vitro models of tissues/diseases and develop regenerative therapies for damaged tissues. Among biopolymers, gelatin and...