Nicole S Verkaik
Overview
Explore the profile of Nicole S Verkaik including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
1433
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Recent Articles
1.
Komar Z, Verkaik N, Dahmani A, Montaudon E, Kanaar R, Houtsmuller A, et al.
NPJ Breast Cancer
. 2025 Feb;
11(1):17.
PMID: 39962055
Breast cancer is the most common cancer amongst women worldwide, however clinically validated chemotherapy response biomarkers that can accurately predict treatment response in patients are largely lacking. Therefore, in this...
2.
Pachler K, Lauwers I, Verkaik N, Rovituso M, van der Wal E, Mast H, et al.
Int J Mol Sci
. 2024 Jul;
25(13).
PMID: 39000262
Radiotherapy in the head-and-neck area is one of the main curative treatment options. However, this comes at the cost of varying levels of normal tissue toxicity, affecting up to 80%...
3.
Meijer T, Martens J, Prager-van der Smissen W, Verkaik N, Beaufort C, van Herk S, et al.
Cancers (Basel)
. 2024 Feb;
16(4).
PMID: 38398132
Tumors with a pathogenic mutation are homologous recombination (HR)-deficient (HRD) and consequently sensitive to platinum-based chemotherapy and Poly-[ADP-Ribose]-Polymerase inhibitors (PARPi). We hypothesized that functional HR status better reflects real-time HR...
4.
Ladan M, Meijer T, Verkaik N, de Monye C, Koppert L, Oomen-de Hoop E, et al.
NPJ Breast Cancer
. 2023 Sep;
9(1):80.
PMID: 37777518
We developed a functional ex vivo anthracycline-based sensitivity test. Surgical resection material of primary breast cancer (BC) was used to determine criteria for the ex vivo sensitivity assay based on...
5.
Reuvers T, Verkaik N, Stuurman D, de Ridder C, Clahsen-van Groningen M, de Blois E, et al.
Theranostics
. 2023 Jun;
13(10):3117-3130.
PMID: 37351169
Peptide receptor radionuclide therapy (PRRT) increases progression-free survival and quality of life of neuroendocrine tumor (NET) patients, however complete cures are rare and dose-limiting toxicity has been reported. PRRT induces...
6.
Feijtel D, Reuvers T, van Tuyll-van Serooskerken C, de Ridder C, Stuurman D, de Blois E, et al.
Cancers (Basel)
. 2023 Feb;
15(3).
PMID: 36765883
Peptide receptor radionuclide therapy (PRRT), a form of internal targeted radiation treatment using [Lu]Lu [DOTA-Tyr]octreotate, is used to treat patients with metastasized neuroendocrine tumors (NETs). Even though PRRT is now...
7.
Capala M, Pachler K, Lauwers I, de Korte M, Verkaik N, Mast H, et al.
Cancers (Basel)
. 2023 Jan;
15(2).
PMID: 36672427
Background: Head and neck squamous cell carcinoma (HNSCC) displays a large heterogeneity in treatment response, and consequently in patient prognosis. Despite extensive efforts, no clinically validated model is available to...
8.
Ruigrok E, Verkaik N, de Blois E, de Ridder C, Stuurman D, Roobol S, et al.
Int J Mol Sci
. 2022 Jul;
23(14).
PMID: 35887398
Prostate specific membrane antigen targeted radionuclide therapy (PSMA-TRT) is a promising novel treatment for prostate cancer (PCa) patients. However, PSMA-TRT cannot be used for curative intent yet, thus additional research...
9.
Meijer T, Nguyen L, Van Hoeck A, Sieuwerts A, Verkaik N, Ladan M, et al.
Oncogene
. 2022 Jun;
41(26):3498-3506.
PMID: 35662281
Germline BRCA1/2 mutation status is predictive for response to Poly-[ADP-Ribose]-Polymerase (PARP) inhibitors in breast cancer (BC) patients. However, non-germline BRCA1/2 mutated and homologous recombination repair deficient (HRD) tumors are likely...
10.
Ladan M, Meijer T, Verkaik N, Komar Z, van Deurzen C, den Bakker M, et al.
Cancers (Basel)
. 2022 Mar;
14(5).
PMID: 35267560
Methods: Ex vivo cisplatin sensitivity assays were established using organotypic tissue slices derived from the surgical resection material of 13 primary BCs and 20 fresh histological biopsies obtained from various...