» Authors » Nicole M Kane

Nicole M Kane

Explore the profile of Nicole M Kane including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 12
Citations 269
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Kane N, Thrasher A, Angelini G, Emanueli C
Stem Cells . 2014 Jan; 32(5):1059-66. PMID: 24449004
MicroRNAs (miRs) are highly conserved, short noncoding RNA molecules that negatively regulate messenger RNA (mRNA) stability and/or translational efficiency. Since a given miR can control the expression of many mRNAs,...
2.
Howard L, Mackenzie R, Pchelintsev N, McBryan T, McClure J, McBride M, et al.
Stem Cell Res Ther . 2013 Apr; 4(2):36. PMID: 23618383
Introduction: Differentiation of vascular endothelial cells (ECs) in clinically relevant numbers for injection into ischaemic areas could offer therapeutic potential in the treatment of cardiovascular conditions, including myocardial infarction, peripheral...
3.
Chick H, Nowrouzi A, Fronza R, McDonald R, Kane N, Alba R, et al.
Hum Gene Ther . 2012 Aug; 23(12):1247-57. PMID: 22931362
We have previously shown that injury-induced neointima formation was rescued by adenoviral-Nogo-B gene delivery. Integrase-competent lentiviral vectors (ICLV) are efficient at gene delivery to vascular cells but present a risk...
4.
White K, Kane N, Milligan G, Baker A
Microcirculation . 2012 Jan; 19(3):196-207. PMID: 22244147
Vascular endothelial cells derived from human pluripotent stem cells have substantial potential for the development of novel vascular therapeutics and cell-based therapies for the repair of ischemic damage. To gain...
5.
Kane N, Howard L, Descamps B, Meloni M, McClure J, Lu R, et al.
Stem Cells . 2012 Jan; 30(4):643-54. PMID: 22232059
MicroRNAs (miRNAs) are short noncoding RNAs, which post-transcriptionally regulate gene expression. miRNAs are transcribed as precursors and matured to active forms by a series of enzymes, including Dicer. miRNAs are...
6.
Howard L, Kane N, Milligan G, Baker A
Vascul Pharmacol . 2011 Aug; 55(4):69-78. PMID: 21854874
Human embryonic stem cells (hESC) offer broad potential for regenerative medicine owing to their capacity for self renewal, exponential scale up and differentiation into any cell type in the adult...
7.
Kane N, Nowrouzi A, Mukherjee S, Blundell M, Greig J, Lee W, et al.
Mol Ther . 2010 Oct; 18(12):2139-45. PMID: 20978477
Retroviral vectors remain the most efficient and widely applied system for induction of pluripotency. However, mutagenic effects have been documented in both laboratory and clinical gene therapy studies, principally as...
8.
Kane N, Xiao Q, Baker A, Luo Z, Xu Q, Emanueli C
Pharmacol Ther . 2010 Oct; 129(1):29-49. PMID: 20965210
Several types of stem and progenitor cells are currently under investigation for their potential to accomplish vascular regeneration. This review focuses on embryonic stem cells (ESCs) and induced pluripotent stem...
9.
Burton P, Adams D, Abraham A, Allcock R, Jiang Z, McCahill A, et al.
Biochem J . 2010 Oct; 432(3):575-84. PMID: 20923411
hESCs (human embryonic stem cells) have enormous potential for use in pharmaceutical development and therapeutics; however, to realize this potential, there is a requirement for simple and reproducible cell culture...
10.
Kane N, Jones M, Brosens J, Kelly R, Saunders P, Critchley H
PLoS One . 2010 Oct; 5(9):e12970. PMID: 20885978
Background: Decidualization (differentiation) of the endometrial stromal cells during the secretory phase of the menstrual cycle is essential for successful implantation. Transforming Growth Factor β1 (TGFβ1) canonically propagates its actions...