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Nicole M Derosia

Explore the profile of Nicole M Derosia including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Lauver M, Katz Z, Markus H, Derosia N, Jin G, Ayers K, et al.
PLoS Pathog . 2025 Mar; 21(3):e1012969. PMID: 40043065
BK polyomavirus (PyV) establishes lifelong asymptomatic infections in the reno-urinary system of most humans. BKPyV-associated nephropathy is the leading infectious cause of kidney allograft loss. Using mouse PyV, a natural...
2.
Milling L, Markson S, Tjokrosurjo Q, Derosia N, Streeter I, Hickok G, et al.
J Exp Med . 2024 Feb; 221(4). PMID: 38411617
In vivo T cell screens are a powerful tool for elucidating complex mechanisms of immunity, yet there is a lack of consensus on the screen design parameters required for robust...
3.
LaFleur M, Lemmen A, Streeter I, Nguyen T, Milling L, Derosia N, et al.
Nat Immunol . 2023 Nov; 25(1):178-188. PMID: 38012416
Annotation of immunologic gene function in vivo typically requires the generation of knockout mice, which is time consuming and low throughput. We previously developed CHimeric IMmune Editing (CHIME), a CRISPR-Cas9...