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Nicole Castano

Explore the profile of Nicole Castano including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Martin-Rufino J, Caulier A, Lee S, Castano N, King E, Joubran S, et al.
bioRxiv . 2024 Sep; PMID: 39314298
Most phenotype-associated genetic variants map to non-coding regulatory regions of the human genome. Moreover, variants associated with blood cell phenotypes are enriched in regulatory regions active during hematopoiesis. To systematically...
2.
Martin-Rufino J, Castano N, Pang M, Grody E, Joubran S, Caulier A, et al.
Cell . 2023 May; 186(11):2456-2474.e24. PMID: 37137305
Systematic evaluation of the impact of genetic variants is critical for the study and treatment of human physiology and disease. While specific mutations can be introduced by genome engineering, we...