Vijay G Sankaran
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Explore the profile of Vijay G Sankaran including associated specialties, affiliations and a list of published articles.
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188
Citations
8171
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Recent Articles
1.
Jayne L, Lavin-Peter A, Roessler J, Tyshkovskiy A, Antoszewski M, Ren E, et al.
Nat Aging
. 2025 Mar;
PMID: 40055478
Torpor and hibernation are extreme physiological adaptations of homeotherms associated with pro-longevity effects. Yet the underlying mechanisms of how torpor affects aging, and whether hypothermic and hypometabolic states can be...
2.
Frenis K, Badalamenti B, Mamigonian O, Weng C, Wang D, Fierstein S, et al.
bioRxiv
. 2025 Feb;
PMID: 39896569
Macrophages play central roles in immunity, wound healing, and homeostasis - a functional diversity that is underpinned by varying developmental origins. The impact of ontogeny on properties of human macrophages...
3.
Jakubek Y, Ma X, Stilp A, Yu F, Bacon J, Wong J, et al.
Am J Hum Genet
. 2025 Jan;
112(2):276-290.
PMID: 39809269
Mosaic loss of Y (mLOY) is the most common somatic chromosomal alteration detected in human blood. The presence of mLOY is associated with altered blood cell counts and increased risk...
4.
Fleming T, Antoszewski M, Lambo S, Gundry M, Piussi R, Wahlster L, et al.
bioRxiv
. 2025 Jan;
PMID: 39803492
Acute myeloid leukemias (AMLs) have an overall poor prognosis with many high-risk cases co-opting stem cell gene regulatory programs, yet the mechanisms through which this occurs remain poorly understood. Increased...
5.
Stenton S, Laricchia K, Lake N, Chaluvadi S, Ganesh V, DiTroia S, et al.
medRxiv
. 2025 Jan;
PMID: 39763565
Background: Variants in the mitochondrial genome (mtDNA) cause a diverse collection of mitochondrial diseases and have extensive phenotypic overlap with Mendelian diseases encoded on the nuclear genome. The mtDNA is...
6.
Hormoz S, Sankaran V, Mullally A
Haematologica
. 2024 Dec;
PMID: 39633553
Over the course of the last decade, genomic studies in the context of normal human hematopoiesis have provided new insights into the early pathogenesis of myeloproliferative neoplasms (MPN). A preclinical...
7.
Liu A, Genovese G, Zhao Y, Pirinen M, Zekavat S, Kentistou K, et al.
Nature
. 2024 Dec;
636(8043):E7.
PMID: 39627447
No abstract available.
8.
Yu Z, Vromman A, Nguyen N, Schuermans A, Rentz T, Vellarikkal S, et al.
bioRxiv
. 2024 Nov;
PMID: 39554199
Plasma proteomic profiles associated with subclinical somatic mutations in blood cells may offer novel insights into downstream clinical consequences. Here, we explore such patterns in clonal hematopoiesis of indeterminate potential...
9.
Voit R, Liao X, Caulier A, Antoszewski M, Cohen B, Armant M, et al.
Cell Stem Cell
. 2024 Nov;
32(1):38-52.e6.
PMID: 39532107
Gene therapy using hematopoietic stem and progenitor cells is altering the therapeutic landscape for patients with hematologic, immunologic, and metabolic disorders but has not yet been successfully developed for individuals...
10.
Borda V, Loesch D, Guo B, Laboulaye R, Veliz-Otani D, French J, et al.
Cell Genom
. 2024 Nov;
4(11):100692.
PMID: 39486408
Latin Americans are underrepresented in genetic studies, increasing disparities in personalized genomic medicine. Despite available genetic data from thousands of Latin Americans, accessing and navigating the bureaucratic hurdles for consent...