Nicole Buchner
Overview
Explore the profile of Nicole Buchner including associated specialties, affiliations and a list of published articles.
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9
Citations
460
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Recent Articles
1.
Haendeler J, Mlynek A, Buchner N, Lukosz M, Graf M, Guettler C, et al.
Arterioscler Thromb Vasc Biol
. 2013 May;
33(7):1639-46.
PMID: 23685552
Objective: Sister-of-Mammalian Grainyhead (SOM) is a member of the Grainyhead family of transcription factors. In humans, 3 isoforms are derived from differential first exon usage and alternative splicing and differ...
2.
Buchner N, Ale-Agha N, Jakob S, Sydlik U, Kunze K, Unfried K, et al.
Exp Gerontol
. 2012 Apr;
48(1):8-16.
PMID: 22507566
Diet and pollution are environmental factors known to compromise "healthy aging" of the cardiovascular and respiratory systems. The molecular consequences of this permanent burden in these cells are still unknown....
3.
Peuschel H, Sydlik U, Haendeler J, Buchner N, Stockmann D, Kroker M, et al.
Biol Chem
. 2010 Sep;
391(11):1327-32.
PMID: 20868224
Owing to their specific physico/chemical properties, engineered as well as environmental nanoparticles can induce pathogenic endpoints in humans. Earlier studies demonstrated that pure carbon nanoparticles induce cell signaling events at...
4.
Buchner N, Zschauer T, Lukosz M, Altschmied J, Haendeler J
Exp Gerontol
. 2010 Mar;
45(7-8):558-62.
PMID: 20211239
Telomerase with its catalytic subunit telomerase reverse transcriptase (TERT) prevents telomere erosion in the nucleus. In addition, telomerase has also telomere-independent functions in protection from apoptosis. Unexpectedly, TERT was found...
5.
Buchner N, Altschmied J, Jakob S, Saretzki G, Haendeler J
Antioxid Redox Signal
. 2009 Dec;
13(4):551-8.
PMID: 19958149
One distinguishing feature of eukaryotic cells is their compartmentalization into organelles, which all have a unique structural and functional identity. Some proteins are exclusively localized in a single organelle, whereas...
6.
Werner C, Furster T, Widmann T, Poss J, Roggia C, Hanhoun M, et al.
Circulation
. 2009 Dec;
120(24):2438-47.
PMID: 19948976
Background: The underlying molecular mechanisms of the vasculoprotective effects of physical exercise are incompletely understood. Telomere erosion is a central component of aging, and telomere-associated proteins regulate cellular senescence and...
7.
Lukosz M, Jakob S, Buchner N, Zschauer T, Altschmied J, Haendeler J
Antioxid Redox Signal
. 2009 Sep;
12(6):713-42.
PMID: 19737086
Reactive oxygen species have been described to modulate proteins within the cell, a process called redox regulation. However, the importance of compartment-specific redox regulation has been neglected for a long...
8.
Haendeler J, Drose S, Buchner N, Jakob S, Altschmied J, Goy C, et al.
Arterioscler Thromb Vasc Biol
. 2009 Mar;
29(6):929-35.
PMID: 19265030
Objective: The enzyme telomerase and its catalytic subunit the telomerase reverse transcriptase (TERT) are important for maintenance of telomere length in the nucleus. Recent studies provided evidence for a mitochondrial...
9.
Jakob S, Schroeder P, Lukosz M, Buchner N, Spyridopoulos I, Altschmied J, et al.
J Biol Chem
. 2008 Oct;
283(48):33155-61.
PMID: 18829466
Aging is one major risk factor for numerous diseases. The enzyme telomerase reverse transcriptase (TERT) plays an important role for aging and apoptosis. Previously, we demonstrated that inhibition of oxidative...