Nicolas Soldermann
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Explore the profile of Nicolas Soldermann including associated specialties, affiliations and a list of published articles.
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15
Citations
303
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Recent Articles
11.
van Eis M, Evenou J, Floersheim P, Gaul C, Cowan-Jacob S, Monovich L, et al.
Bioorg Med Chem Lett
. 2011 Nov;
21(24):7367-72.
PMID: 22078216
The present study describes a novel series of ATP-competitive PKC inhibitors based on the 2,6-naphthyridine template. Example compounds potently inhibit the novel Protein Kinase C (PKC) isotypes δ, ε, η,...
12.
Gamber G, Meredith E, Zhu Q, Yan W, Rao C, Capparelli M, et al.
Bioorg Med Chem Lett
. 2011 Feb;
21(5):1447-51.
PMID: 21300545
The synthesis and preliminary studies of the SAR of novel 3,5-diarylazole inhibitors of Protein Kinase D (PKD) are reported. Notably, optimized compounds in this class have been found to be...
13.
Meredith E, Beattie K, Burgis R, Capparelli M, Chapo J, DiPietro L, et al.
J Med Chem
. 2010 Aug;
53(15):5422-38.
PMID: 20684592
The synthesis and biological evaluation of potent and selective PKD inhibitors are described herein. The compounds described in the present study selectively inhibit PKD among other putative HDAC kinases. The...
14.
Wender P, Hilinski M, Soldermann N, Mooberry S
Org Lett
. 2006 Mar;
8(7):1507-10.
PMID: 16562928
[reaction: see text] A step-economical synthesis of 11-desmethyllaulimalide (2) is reported. This simplified analogue is available through an improved second-generation synthetic approach to the laulimalides, in a shorter step count...
15.
Khaledy M, Kalani M, Khuong K, Houk K, Aviyente V, Neier R, et al.
J Org Chem
. 2003 Jan;
68(2):572-7.
PMID: 12530884
The relative energies of the chair and boat transition states of a variety of Ireland-Claisen rearrangements were obtained by B3LYP/6-31G calculations. Theoretical results are in good agreement with experimental data...