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Nicolas Chevrier

Explore the profile of Nicolas Chevrier including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 1802
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Recent Articles
1.
Cipurko D, Ueda T, Mei L, Chevrier N
Nat Methods . 2024 Nov; 22(1):145-155. PMID: 39562752
Spatiomolecular analyses are key to study tissue functions and malfunctions. However, we lack profiling tools for spatial transcriptomics that are easy to adopt, low cost and scalable in terms of...
2.
Takahama M, Patil A, Richey G, Cipurko D, Johnson K, Carbonetto P, et al.
Nat Immunol . 2024 Jan; 25(2):226-239. PMID: 38191855
Sepsis is a systemic response to infection with life-threatening consequences. Our understanding of the molecular and cellular impact of sepsis across organs remains rudimentary. Here, we characterize the pathogenesis of...
3.
Takahama M, Patil A, Johnson K, Cipurko D, Miki Y, Taketomi Y, et al.
bioRxiv . 2023 Feb; PMID: 36778287
Sepsis is a systemic response to infection with life-threatening consequences. Our understanding of the impact of sepsis across organs of the body is rudimentary. Here, using mouse models of sepsis,...
4.
Bessa-Neto D, Beliu G, Kuhlemann A, Pecoraro V, Doose S, Retailleau N, et al.
Nat Commun . 2021 Nov; 12(1):6715. PMID: 34795271
Progress in biological imaging is intrinsically linked to advances in labeling methods. The explosion in the development of high-resolution and super-resolution imaging calls for new approaches to label targets with...
5.
Pandey S, Gruenbaum A, Kanashova T, Mertins P, Cluzel P, Chevrier N
Cell Syst . 2020 Oct; 11(5):495-508.e10. PMID: 33113356
The immune system makes decisions in response to combinations of multiple microbial inputs. We do not understand the combinatorial logic governing how higher-order combinations of microbial signals shape immune responses....
6.
Chevrier N
Curr Opin Syst Biol . 2020 Jun; 18:19-26. PMID: 32490290
The immune system is a dynamic mesh of molecules, cells and tissues spanning the entire organism. Despite a wealth of knowledge about the components of the immune system, little is...
7.
Pandey S, Takahama M, Gruenbaum A, Zewde M, Cheronis K, Chevrier N
Nat Protoc . 2020 Feb; 15(4):1459-1483. PMID: 32076350
The immune system operates at the scale of the whole organism in mammals. We currently lack experimental approaches to systematically track and study organism-wide molecular processes in mice. Here we...
8.
Kadoki M, Patil A, Thaiss C, Brooks D, Pandey S, Deep D, et al.
Cell . 2017 Sep; 171(2):398-413.e21. PMID: 28942919
A fundamental challenge in immunology is to decipher the principles governing immune responses at the whole-organism scale. Here, using a comparative infection model, we observe immune signal propagation within and...
9.
Mertins P, Przybylski D, Yosef N, Qiao J, Clauser K, Raychowdhury R, et al.
Cell Rep . 2017 Jun; 19(13):2853-2866. PMID: 28658630
Building an integrated view of cellular responses to environmental cues remains a fundamental challenge due to the complexity of intracellular networks in mammalian cells. Here, we introduce an integrative biochemical...
10.
Sage P, Ron-Harel N, Juneja V, Sen D, Maleri S, Sungnak W, et al.
Nat Immunol . 2016 Oct; 17(12):1436-1446. PMID: 27695002
Follicular regulatory T cells (T cells) inhibit follicular helper T cell (T cell)-mediated antibody production. The mechanisms by which T cells exert their key immunoregulatory functions are largely unknown. Here...