Nicolas Broguiere
Overview
Explore the profile of Nicolas Broguiere including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
27
Citations
960
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Dutta D, Lorenzo-Martin L, Rivest F, Broguiere N, Tillard L, Ragusa S, et al.
NPJ Precis Oncol
. 2024 Aug;
8(1):179.
PMID: 39143103
Immunotherapy has emerged as a new standard of care for certain cancer patients with specific cellular and molecular makeups. However, there is still an unmet need for ex vivo models...
2.
Lorenzo-Martin L, Broguiere N, Langer J, Tillard L, Nikolaev M, Coukos G, et al.
Nat Biotechnol
. 2024 Jul;
PMID: 38956326
Existing organoid models fall short of fully capturing the complexity of cancer because they lack sufficient multicellular diversity, tissue-level organization, biological durability and experimental flexibility. Thus, many multifactorial cancer processes,...
3.
Liu Y, Ansaryan S, Tan J, Broguiere N, Lorenzo-Martin L, Homicsko K, et al.
Adv Sci (Weinh)
. 2024 Jun;
11(34):e2401539.
PMID: 38924371
Organoid tumor models have emerged as a powerful tool in the fields of biology and medicine as such 3D structures grown from tumor cells recapitulate better tumor characteristics, making these...
4.
Mitrofanova O, Nikolaev M, Xu Q, Broguiere N, Cubela I, Camp J, et al.
Cell Stem Cell
. 2024 Jun;
31(8):1175-1186.e7.
PMID: 38876106
Organoids and organs-on-a-chip have emerged as powerful tools for modeling human gut physiology and disease in vitro. Although physiologically relevant, these systems often lack the environmental milieu, spatial organization, cell...
5.
Lorenzo-Martin L, Hubscher T, Bowler A, Broguiere N, Langer J, Tillard L, et al.
Nature
. 2024 Apr;
629(8011):450-457.
PMID: 38658753
Three-dimensional organoid culture technologies have revolutionized cancer research by allowing for more realistic and scalable reproductions of both tumour and microenvironmental structures. This has enabled better modelling of low-complexity cancer...
6.
Girgin M, Broguiere N, Mattolini L, Lutolf M
Bio Protoc
. 2023 Jul;
13(14):e4722.
PMID: 37497450
Embryonic development is a complex process integrating cell fate decisions and morphogenesis in a spatiotemporally controlled manner. Previous studies with model organisms laid the foundation of our knowledge on post-implantation...
7.
Gonzalez D, Schrode N, Ebrahim T, Broguiere N, Rossi G, Drakhlis L, et al.
Development
. 2022 Jun;
149(13).
PMID: 35686629
The specification of distinct cardiac lineages occurs before chamber formation and acquisition of bona fide atrial or ventricular identity. However, the mechanisms underlying these early specification events remain poorly understood....
8.
Chrisnandy A, Blondel D, Rezakhani S, Broguiere N, Lutolf M
Nat Mater
. 2021 Nov;
21(4):479-487.
PMID: 34782747
Epithelial organoids are most efficiently grown from mouse-tumour-derived, reconstituted extracellular matrix hydrogels, whose poorly defined composition, batch-to-batch variability and immunogenicity limit clinical applications. Efforts to replace such ill-defined matrices for...
9.
Girgin M, Broguiere N, Hoehnel S, Brandenberg N, Mercier B, Martinez Arias A, et al.
Nat Commun
. 2021 Aug;
12(1):5140.
PMID: 34446708
The difficulty of studying post-implantation development in mammals has sparked a flurry of activity to develop in vitro models, termed embryoids, based on self-organizing pluripotent stem cells. Previous approaches to...
10.
LeSavage B, Suhar R, Broguiere N, Lutolf M, Heilshorn S
Nat Mater
. 2021 Aug;
21(2):143-159.
PMID: 34385685
Organotypic models of patient-specific tumours are revolutionizing our understanding of cancer heterogeneity and its implications for personalized medicine. These advancements are, in part, attributed to the ability of organoid models...